Puma Biotechnology Inc (PBYI)
PBYI moved a median of +0.44% 30 minutes after news, and +0.16% by the close. How PBYI actually reacts to news — the realized, point-in-time move the market made, measured across 274 labeled events over the last three years with zero look-ahead.
PBYI’s median reaction, across the day.
| Horizon | Median | % positive | Events |
|---|---|---|---|
| 5-min | +0.13% | 52% | 272 |
| 30-min | +0.44% | 55% | 274 |
| 60-min | -0.07% | 47% | 274 |
| to close | +0.16% | 50% | 274 |
| Middle 50% of PBYI reactions | -1.13% to +2.18% |
|---|---|
| Median reaction (30-min) | +0.44% |
| Measured reactions | 274 |
Half of all Puma Biotechnology Inc news events land between -1.13% and +2.18% at 30 minutes.
Reaction stats as of 2026-09-21. Newest measured event . Reaction = percent move vs. the price at the news timestamp.
How PBYI reacts, by analyst action.
| Event | Events | Median 30-min | % positive | Median to close |
|---|---|---|---|---|
| Analyst upgrades | 19 | -1.38% | 32% | -0.69% |
| Analyst downgrades | 11 | +0.85% | 55% | -0.66% |
| Rating reiterations | 22 | +0.07% | 50% | +0.16% |
Last 3 years, pulled 2026-09-21. Reaction = percent move vs. the price at the news timestamp. Counts and medians only. The same measurement runs across every name in the dataset. 2 further classes were observed with fewer than 10 measured events and are not published. See how PBYI ranks against every other measured name →
That’s how PBYI usually reacts — get an email when it moves on news →Email me when PBYI moves on news.
One email per qualifying move — the headline, the measured reaction, and how it compares to PBYI's baseline. Nothing else.
Recent PBYI events, each with its measured reaction.
| Date | Headline | Event | Source | 5-min | To close |
|---|---|---|---|---|---|
| Puma Biotechnology Reports Inducement Award Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | -1.03% | -2.26% | |
| Puma Biotechnology Initiates ALISCA®-Lung2, a Phase II Trial of Alisertib in Combination with Paclitaxel for the Treatment of Patients with Advanced Small Cell Lung Cancer | Press release | Business Wire | -0.37% | +0.84% | |
| Puma Biotechnology to Present at H.C. Wainwright’s 28th Annual Global Investment Conference | Press release | Business Wire | -0.44% | +1.78% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.21% | +1.60% | |
| Form 10-Q PUMA BIOTECHNOLOGY, INC. For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | +8.72% | +9.73% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Aug 06 | SEC filing · Form 8-K | SEC EDGAR | +8.72% | +9.73% | |
| Puma Biotechnology Reports Second Quarter 2026 Financial Results | Press release | Business Wire | +8.72% | +9.73% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | -1.25% | +1.25% | |
| Puma Biotechnology to Host Conference Call to Discuss Second Quarter 2026 Financial Results | Press release | Business Wire | -0.31% | -0.87% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.85% | -0.48% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Jun 11 | SEC filing · Form 8-K | SEC EDGAR | +1.12% | +0.98% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.00% | +2.94% | |
| Form 10-Q PUMA BIOTECHNOLOGY, INC. For: Mar 31 | SEC filing · Form 10-Q | SEC EDGAR | +3.07% | +4.46% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: May 07 | SEC filing · Form 8-K | SEC EDGAR | +3.07% | +4.46% | |
| Puma Biotechnology Reports First Quarter 2026 Financial Results | Press release | Business Wire | +3.07% | +4.46% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | -0.67% | -3.46% | |
| Form ARS PUMA BIOTECHNOLOGY, INC. For: Dec 31 | SEC filing · Form ARS | SEC EDGAR | -0.67% | -0.40% | |
| Form DEF 14A PUMA BIOTECHNOLOGY, INC. For: Jun 11 | SEC filing · Form DEF | SEC EDGAR | -0.67% | -0.40% | |
| Form DEFA14A PUMA BIOTECHNOLOGY, INC. | SEC filing · Form DEFA14A | SEC EDGAR | -0.67% | -0.40% | |
| Puma Biotechnology to Host Conference Call to Discuss First Quarter 2026 Financial Results | Press release | Business Wire | +0.00% | +1.75% | |
| Form PRE 14A PUMA BIOTECHNOLOGY, INC. For: Jun 11 | SEC filing · Form PRE | SEC EDGAR | -0.28% | +4.74% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.14% | -0.43% | |
| Form 10-K PUMA BIOTECHNOLOGY, INC. For: Dec 31 | SEC filing · Form 10-K | SEC EDGAR | +2.70% | -9.52% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Feb 26 | SEC filing · Form 8-K | SEC EDGAR | +2.70% | -9.52% | |
| Puma Biotechnology Reports Fourth Quarter and Full Year 2025 Financial Results | Press release | Business Wire | +2.70% | -9.52% | |
| Puma Biotechnology to Present at TD Cowen’s 46th Annual Health Care Conference | Press release | Business Wire | +1.12% | +5.05% | |
| Puma Biotechnology to Host Conference Call to Discuss Fourth Quarter and Full Year 2025 Financial Results | Press release | Business Wire | +1.55% | +0.44% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.71% | -3.14% | |
| New Breast Cancer Therapy to Reduce Risk of Recurrence and Improve Disease-Free Survival Now Available in Thailand | Press release | PR Newswire | +0.07% | -1.15% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.33% | +1.81% | |
| Puma Biotechnology Added to the NASDAQ Biotechnology Index (NBI) | Press release | Business Wire | +1.04% | +2.07% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | -0.51% | +5.92% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.83% | -21.04% | |
| Form 10-Q PUMA BIOTECHNOLOGY, INC. For: Sep 30 | SEC filing · Form 10-Q | SEC EDGAR | -0.38% | +12.38% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Nov 06 | SEC filing · Form 8-K | SEC EDGAR | -0.38% | +12.38% | |
| Puma Biotechnology Reports Third Quarter 2025 Financial Results | Press release | Business Wire | -0.38% | +12.38% | |
| Puma Biotechnology to Host Conference Call to Discuss Third Quarter Financial Results | Press release | Business Wire | +1.18% | +2.75% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +1.15% | -2.10% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | -0.39% | -2.52% | |
| Puma Biotechnology to Present at the H.C. Wainwright 27th Annual Global Investment Conference | Press release | Business Wire | +0.98% | +0.59% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +6.67% | +30.38% | |
| Form 10-Q PUMA BIOTECHNOLOGY, INC. For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | +10.16% | +20.98% | |
| Form 10-Q/A PUMA BIOTECHNOLOGY, INC. For: Mar 31 | SEC filing · Form 10-Q | SEC EDGAR | -1.22% | +0.00% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Aug 07 | SEC filing · Form 8-K | SEC EDGAR | +10.16% | +20.98% | |
| Puma Biotechnology Reports Second Quarter Financial Results | Press release | Business Wire | +10.16% | +20.98% | |
| Puma Biotechnology to Host Conference Call to Discuss Second Quarter 2025 Financial Results | Press release | Business Wire | -3.82% | -3.53% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | +0.28% | +0.56% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Jun 19 | SEC filing · Form 8-K | SEC EDGAR | -1.06% | -2.07% | |
| Form 8-K PUMA BIOTECHNOLOGY, INC. For: Jun 11 | SEC filing · Form 8-K | SEC EDGAR | -1.18% | +1.47% | |
| Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) | Press release | Business Wire | -1.54% | +2.53% |
Each reaction is the move the market actually made, measured from the news timestamp. Headlines link through to the PBYI section they belong to.
Where else PBYI is measured.
PBYI earnings → · Analyst actions → · SEC filings →
Other Healthcare names, measured the same way
| Ticker | Events | Median 30-min | % positive |
|---|---|---|---|
| Evolus, Inc. (EOLS) | 275 | +0.08% | 51% |
| LivaNova PLC - Ordinary Shares (LIVN) | 275 | +0.04% | 51% |
| PRANA BIOTECH (PRAN) | 274 | 0.00% | 48% |
| Solana Company - Class A (HSDT) | 272 | -1.20% | 37% |
Same sector, same measurement: percent move vs. the price at the news timestamp, read at 30 minutes. Sample sizes differ, so the medians are comparable but the confidence behind them is not.
All Healthcare names, measured the same way →
Every ticker we measure the same way24
Apple (AAPL)
How AAPL actually reacts to news, measured.
NVIDIA (NVDA)
How NVDA actually reacts to news, measured.
Tesla (TSLA)
How TSLA actually reacts to news, measured.
Microsoft (MSFT)
How MSFT actually reacts to news, measured.
Advanced Micro Devices (AMD)
How AMD actually reacts to news, measured.
Amazon (AMZN)
How AMZN actually reacts to news, measured.
Alphabet (GOOG)
How GOOG actually reacts to news, measured.
Meta Platforms (META)
How META actually reacts to news, measured.
Broadcom (AVGO)
How AVGO actually reacts to news, measured.
JPMorgan Chase (JPM)
How JPM actually reacts to news, measured.
Visa (V)
How V actually reacts to news, measured.
Walmart (WMT)
How WMT actually reacts to news, measured.
Eli Lilly (LLY)
How LLY actually reacts to news, measured.
UnitedHealth Group (UNH)
How UNH actually reacts to news, measured.
Netflix (NFLX)
How NFLX actually reacts to news, measured.
Johnson & Johnson (JNJ)
How JNJ actually reacts to news, measured.
Exxon Mobil (XOM)
How XOM actually reacts to news, measured.
Home Depot (HD)
How HD actually reacts to news, measured.
Costco (COST)
How COST actually reacts to news, measured.
Mastercard (MA)
How MA actually reacts to news, measured.
Oracle (ORCL)
How ORCL actually reacts to news, measured.
Salesforce (CRM)
How CRM actually reacts to news, measured.
Bank of America (BAC)
How BAC actually reacts to news, measured.
Coca-Cola (KO)
How KO actually reacts to news, measured.
Walt Disney (DIS)
How DIS actually reacts to news, measured.
Browse all tickers
Every name we’ve measured, in one place.
How the numbers are made.
How is Puma Biotechnology Inc's median reaction calculated?
Every labeled PBYI news event is measured from its own timestamp: the last trade before the news is the base price, and the move is read at fixed horizons — 30 minutes of trading, then the close. The median across 274 events is what this page reports. Point-in-time, zero look-ahead: no event borrows information from a later one.
What counts as a positive reaction?
Any event whose price move is above zero at the horizon, relative to the last trade before the news timestamp. 55% of PBYI's measured events are up at 30 minutes; the rest close the window flat or negative.
How often is this page updated?
The news table refreshes automatically as new events are labeled and priced. The reaction medians are re-pulled in batches from the dataset — the figures here are as of 2026-09-21.
Does PBYI's past reaction predict its next one?
No. These are realized facts about past events, not forecasts. They describe a distribution — they say nothing certain about any future move.