Opko Health, Inc. (OPK)
OPK moved a median of 0.00% 30 minutes after news, and +0.59% by the close. How OPK actually reacts to news — the realized, point-in-time move the market made, measured across 230 labeled events over the last three years with zero look-ahead.
OPK’s median reaction, across the day.
| Horizon | Median | % positive | Events |
|---|---|---|---|
| 5-min | 0.00% | 48% | 229 |
| 30-min | 0.00% | 51% | 229 |
| 60-min | 0.00% | 47% | 229 |
| to close | +0.59% | 51% | 230 |
| Middle 50% of OPK reactions | -0.84% to +1.84% |
|---|---|
| Median reaction (30-min) | 0.00% |
| Measured reactions | 230 |
Half of all Opko Health, Inc. news events land between -0.84% and +1.84% at 30 minutes.
Reaction stats as of 2026-09-21. Newest measured event . Reaction = percent move vs. the price at the news timestamp.
How OPK reacts, by analyst action.
| Event | Events | Median 30-min | % positive | Median to close |
|---|---|---|---|---|
| Analyst upgrades | 14 | +0.92% | 64% | 0.00% |
| Analyst downgrades | 13 | -0.37% | 23% | -3.29% |
| Rating reiterations | 44 | +0.33% | 55% | +1.15% |
Last 3 years, pulled 2026-09-21. Reaction = percent move vs. the price at the news timestamp. Counts and medians only. The same measurement runs across every name in the dataset. 3 further classes were observed with fewer than 10 measured events and are not published. See how OPK ranks against every other measured name →
That’s how OPK usually reacts — get an email when it moves on news →Email me when OPK moves on news.
One email per qualifying move — the headline, the measured reaction, and how it compares to OPK's baseline. Nothing else.
Recent OPK events, each with its measured reaction.
| Date | Headline | Event | Source | 5-min | To close |
|---|---|---|---|---|---|
| Form 8-K OPKO HEALTH, INC. For: Oct 14 | SEC filing · Form 8-K | SEC EDGAR | +0.29% | -11.56% | |
| Form 8-K OPKO HEALTH, INC. For: Sep 30 | SEC filing · Form 8-K | SEC EDGAR | -0.26% | +1.29% | |
| OPKO Health to Participate in the Wells Fargo 21st Annual Healthcare Conference | Press release | GlobeNewswire | +0.00% | +2.25% | |
| Form 10-Q/A OPKO HEALTH, INC. For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | -0.06% | -0.68% | |
| Form 10-Q/A OPKO HEALTH, INC. For: Mar 31 | SEC filing · Form 10-Q | SEC EDGAR | -0.06% | -0.68% | |
| Form 8-K OPKO HEALTH, INC. For: Aug 13 | SEC filing · Form 8-K | SEC EDGAR | +1.11% | +0.74% | |
| OPKO Health Expands Strategic Relationship with HealthCare Royalty Through $125 Million Notes Issuance Secured by Mazdutide Royalty Interests | Press release | GlobeNewswire | +0.71% | -0.71% | |
| Form 10-Q OPKO HEALTH, INC. For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | +7.25% | +19.57% | |
| Form 8-K OPKO HEALTH, INC. For: Jul 27 | SEC filing · Form 8-K | SEC EDGAR | +7.25% | +19.57% | |
| OPKO Health Reports Second Quarter 2026 Business Highlights and Financial Results | Press release | GlobeNewswire | +7.25% | +19.57% | |
| OPKO Health to Report Second Quarter 2026 Financial Results on July 27, 2026 | Press release | GlobeNewswire | +0.00% | -1.27% | |
| Form 8-K OPKO HEALTH, INC. For: Jun 18 | SEC filing · Form 8-K | SEC EDGAR | +1.41% | +0.70% | |
| Preclinical Data for OPKO Biologics' OPK8801001 in Acromegaly Presented at ENDO 2026 | Press release | GlobeNewswire | -1.62% | -2.10% | |
| Form DEFA14A OPKO HEALTH, INC. | SEC filing · Form DEFA14A | SEC EDGAR | +2.29% | +3.67% | |
| OPKO Health’s ModeX Therapeutics Will Present Data Demonstrating In Vivo CAR-T Cell Generation and Deep B-Cell Depletion in Preclinical Studies | Press release | GlobeNewswire | +0.00% | -1.79% | |
| BioReference® Launches BioReference Direct™, Expanding Access to Consumer-Initiated Diagnostic Testing Through a Fully Integrated Digital Platform | Press release | GlobeNewswire | +0.01% | +2.27% | |
| Form ARS OPKO HEALTH, INC. For: Dec 31 | SEC filing · Form ARS | SEC EDGAR | +0.44% | -2.65% | |
| Form DEF 14A OPKO HEALTH, INC. For: Apr 30 | SEC filing · Form DEF | SEC EDGAR | +0.44% | -2.65% | |
| Form DEFA14A OPKO HEALTH, INC. | SEC filing · Form DEFA14A | SEC EDGAR | +0.44% | -2.65% | |
| OPKO Health Expands Nicoya Agreement to Support RAYALDEE® Commercialization in Greater China | Press release | GlobeNewswire | +0.01% | +2.27% | |
| Form 10-Q OPKO HEALTH, INC. For: Mar 31 | SEC filing · Form 10-Q | SEC EDGAR | -5.13% | -5.13% | |
| Form 8-K OPKO HEALTH, INC. For: Apr 28 | SEC filing · Form 8-K | SEC EDGAR | -5.13% | -5.13% | |
| OPKO Health Reports First Quarter 2026 Business Highlights and Financial Results | Press release | GlobeNewswire | -5.13% | -5.13% | |
| OPKO Health’s ModeX Therapeutics Begins Clinical Trial of Tetraspecific Antibody for Treatment of B-cell Lymphomas | Press release | GlobeNewswire | +0.82% | +0.82% | |
| OPKO Health to Report First Quarter 2026 Financial Results on April 28, 2026 | Press release | GlobeNewswire | +0.82% | +0.82% | |
| OPKO Health’s ModeX Therapeutics Initiates Clinical Trial of MDX2301 for the Prevention of COVID-19 | Press release | GlobeNewswire | +1.25% | -0.83% | |
| Form 8-K OPKO HEALTH, INC. For: Mar 18 | SEC filing · Form 8-K | SEC EDGAR | +0.09% | -3.45% | |
| OPKO Health to Participate in the Jefferies Biotech on the Beach Summit | Press release | GlobeNewswire | +1.26% | +0.84% | |
| Form 10-K OPKO HEALTH, INC. For: Dec 31 | SEC filing · Form 10-K | SEC EDGAR | +1.26% | +0.84% | |
| Form 8-K OPKO HEALTH, INC. For: Feb 26 | SEC filing · Form 8-K | SEC EDGAR | +1.26% | +0.84% | |
| OPKO Health Reports Fourth Quarter 2025 Business Highlights and Financial Results | Press release | GlobeNewswire | +1.26% | +0.84% | |
| OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26 | Press release | GlobeNewswire | -0.40% | -3.20% | |
| OPKO Health and Entera Bio Expand Partnership to Advance First-in-Class Oral Long Acting PTH Tablet for Patients with Hypoparathyroidism | Press release | GlobeNewswire | -0.39% | -1.57% | |
| OPKO Health to Participate in the 44th Annual J.P. Morgan Healthcare Conference | Press release | GlobeNewswire | -0.75% | +2.26% | |
| OPKO Health to Participate in the Piper Sandler 37th Annual Healthcare Conference | Press release | GlobeNewswire | +0.38% | -1.51% | |
| Form 10-Q OPKO HEALTH, INC. For: Sep 30 | SEC filing · Form 10-Q | SEC EDGAR | +1.55% | +4.29% | |
| Form 8-K OPKO HEALTH, INC. For: Oct 29 | SEC filing · Form 8-K | SEC EDGAR | +1.55% | +4.29% | |
| OPKO Health Reports Third Quarter 2025 Business Highlights and Financial Results | Press release | GlobeNewswire | +1.55% | +4.29% | |
| OPKO Health’s ModeX Therapeutics Enters into Research Collaboration with Regeneron to Develop Multispecific Antibodies for Select Therapeutic Indications | Press release | GlobeNewswire | -0.35% | -0.69% | |
| OPKO Health’s ModeX Therapeutics Begins Clinical Trial of MDX2004 for the Treatment of Advanced Cancers | Press release | GlobeNewswire | -0.34% | -0.69% | |
| Greenberg Traurig Selected as Winner at 2025 Beacon Awards in Professional Services Category | Press release | PR Web | -0.34% | -1.70% | |
| OPKO Health to Report Third Quarter 2025 Financial Results on October 29 | Press release | GlobeNewswire | -0.33% | +1.33% | |
| Form 8-K OPKO HEALTH, INC. For: Sep 15 | SEC filing · Form 8-K | SEC EDGAR | +1.02% | +1.46% | |
| Form 10-Q OPKO HEALTH, INC. For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | -3.66% | -3.25% | |
| Form 8-K OPKO HEALTH, INC. For: Jul 31 | SEC filing · Form 8-K | SEC EDGAR | -3.66% | -3.25% | |
| OPKO Health Reports Second Quarter 2025 Business Highlights and Financial Results | Press release | GlobeNewswire | -3.66% | -3.25% | |
| OPKO Health to Report Second Quarter 2025 Financial Results on July 31 | Press release | GlobeNewswire | -1.09% | -0.72% | |
| OPKO Health and Entera Bio Announce Abstract on PK/PD of Oral GLP-2 Tablet for the Treatment of Short Bowel Syndrome Selected for 2025 ESPEN Congress | Press release | GlobeNewswire | +0.37% | +0.00% | |
| OPKO Health and Entera Bio Abstract for First-in-Class Dual GLP-1/Glucagon Tablet Candidate for Patients with Obesity and Metabolic Disorders Selected for Presentation at the ENDO 2025 Annual Meeting | Press release | GlobeNewswire | +0.39% | -2.31% | |
| OPKO Health to Participate in the 3rd Annual Piper Sandler Virtual Obesity Symposium | Press release | GlobeNewswire | +0.00% | -1.17% |
Each reaction is the move the market actually made, measured from the news timestamp. Headlines link through to the OPK section they belong to.
Where else OPK is measured.
OPK earnings → · Analyst actions → · SEC filings →
Other Healthcare names, measured the same way
| Ticker | Events | Median 30-min | % positive |
|---|---|---|---|
| Cronos Group Inc. - Common Share (CRON) | 230 | +0.27% | 62% |
| Forward Pharma A/S - American Depositary Shares (FWP) | 230 | 0.00% | 37% |
| Veru Inc. (VERU) | 230 | -0.47% | 43% |
| iRadimed Corporation (IRMD) | 229 | +0.10% | 55% |
Same sector, same measurement: percent move vs. the price at the news timestamp, read at 30 minutes. Sample sizes differ, so the medians are comparable but the confidence behind them is not.
All Healthcare names, measured the same way →
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Every name we’ve measured, in one place.
How the numbers are made.
How is Opko Health, Inc.'s median reaction calculated?
Every labeled OPK news event is measured from its own timestamp: the last trade before the news is the base price, and the move is read at fixed horizons — 30 minutes of trading, then the close. The median across 230 events is what this page reports. Point-in-time, zero look-ahead: no event borrows information from a later one.
What counts as a positive reaction?
Any event whose price move is above zero at the horizon, relative to the last trade before the news timestamp. 51% of OPK's measured events are up at 30 minutes; the rest close the window flat or negative.
How often is this page updated?
The news table refreshes automatically as new events are labeled and priced. The reaction medians are re-pulled in batches from the dataset — the figures here are as of 2026-09-21.
Does OPK's past reaction predict its next one?
No. These are realized facts about past events, not forecasts. They describe a distribution — they say nothing certain about any future move.