OnKure Therapeutics, Inc. - Class A (OKUR)
OKUR moved a median of -1.15% 30 minutes after news, and -1.13% by the close. How OKUR actually reacts to news — the realized, point-in-time move the market made, measured across 194 labeled events over the last three years with zero look-ahead.
OKUR’s median reaction, across the day.
| Horizon | Median | % positive | Events |
|---|---|---|---|
| 5-min | 0.00% | 38% | 163 |
| 30-min | -1.15% | 37% | 192 |
| 60-min | -0.90% | 36% | 194 |
| to close | -1.13% | 40% | 193 |
| Middle 50% of OKUR reactions | -2.26% to +1.74% |
|---|---|
| Median reaction (30-min) | -1.15% |
| Measured reactions | 194 |
Half of all OnKure Therapeutics, Inc. - Class A news events land between -2.26% and +1.74% at 30 minutes.
Reaction stats as of 2026-09-21. Newest measured event . Reaction = percent move vs. the price at the news timestamp.
How OKUR reacts, by analyst action.
| Event | Events | Median 30-min | % positive | Median to close |
|---|---|---|---|---|
| Coverage initiations | 12 | -0.19% | 42% | +1.18% |
| Rating reiterations | 12 | +0.01% | 50% | +1.05% |
Last 3 years, pulled 2026-09-21. Reaction = percent move vs. the price at the news timestamp. Counts and medians only. The same measurement runs across every name in the dataset. 3 further classes were observed with fewer than 10 measured events and are not published. See how OKUR ranks against every other measured name →
That’s how OKUR usually reacts — get an email when it moves on news →Email me when OKUR moves on news.
One email per qualifying move — the headline, the measured reaction, and how it compares to OKUR's baseline. Nothing else.
Recent OKUR events, each with its measured reaction.
| Date | Headline | Event | Source | 5-min | To close |
|---|---|---|---|---|---|
| OnKure Therapeutics to Participate in the Morgan Stanley Global Healthcare Conference | Press release | GlobeNewswire | +0.40% | -4.47% | |
| Form 8-K OnKure Therapeutics, For: Aug 07 | SEC filing · Form 8-K | SEC EDGAR | +0.25% | -1.27% | |
| Form 10-Q OnKure Therapeutics, For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | -0.48% | +0.73% | |
| Form 8-K OnKure Therapeutics, For: Aug 04 | SEC filing · Form 8-K | SEC EDGAR | -0.48% | +0.73% | |
| OnKure Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Highlights | Press release | GlobeNewswire | -0.48% | +0.73% | |
| OnKure Therapeutics to Host Virtual KOL Event to Discuss PI3Ka Inhibitor Medicines: Selectivity Matters & Pan-Mutant Allosteric Inhibition Delivers, on July 15, 2026 | Press release | GlobeNewswire | -1.57% | +2.69% | |
| Form S-8 OnKure Therapeutics, | SEC filing · Form S-8 | SEC EDGAR | +3.79% | +4.26% | |
| Form 8-K OnKure Therapeutics, For: Jun 03 | SEC filing · Form 8-K | SEC EDGAR | +2.67% | -2.56% | |
| Form 10-Q OnKure Therapeutics, For: Mar 31 | SEC filing · Form 10-Q | SEC EDGAR | -6.45% | -6.22% | |
| Form 8-K OnKure Therapeutics, For: May 05 | SEC filing · Form 8-K | SEC EDGAR | -6.45% | -6.22% | |
| Form EFFECT OnKure Therapeutics, | SEC filing · Form EFFECT | SEC EDGAR | -1.72% | -2.80% | |
| OnKure Therapeutics Reports First Quarter 2026 Financial Results | Press release | GlobeNewswire | -6.45% | -6.22% | |
| Form S-3 OnKure Therapeutics, | SEC filing · Form S-3 | SEC EDGAR | +0.00% | +3.96% | |
| Form ARS OnKure Therapeutics, For: Dec 31 | SEC filing · Form ARS | SEC EDGAR | +0.20% | +2.04% | |
| Form DEF 14A OnKure Therapeutics, For: Jun 03 | SEC filing · Form DEF | SEC EDGAR | +0.20% | +2.04% | |
| Form DEFA14A OnKure Therapeutics, | SEC filing · Form DEFA14A | SEC EDGAR | +0.20% | +2.04% | |
| Form 8-K OnKure Therapeutics, For: Mar 27 | SEC filing · Form 8-K | SEC EDGAR | -1.63% | -4.77% | |
| OnKure Therapeutics Announces Oversubscribed $150 Million Private Placement to Advance Next-Generation PI3Ka Pan-Mutant Selective Inhibitor Candidates in Breast Cancer and Vascular Anomalies | Press release | GlobeNewswire | -2.04% | +1.53% | |
| Form 10-K OnKure Therapeutics, For: Dec 31 | SEC filing · Form 10-K | SEC EDGAR | -2.94% | +1.07% | |
| Form 8-K OnKure Therapeutics, For: Mar 12 | SEC filing · Form 8-K | SEC EDGAR | -2.94% | +1.07% | |
| Form S-8 OnKure Therapeutics, | SEC filing · Form S-8 | SEC EDGAR | -2.94% | +1.07% | |
| OnKure Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results | Press release | GlobeNewswire | -2.94% | +1.07% | |
| Form EFFECT OnKure Therapeutics, | SEC filing · Form EFFECT | SEC EDGAR | — | -7.07% | |
| Form 10-Q OnKure Therapeutics, For: Sep 30 | SEC filing · Form 10-Q | SEC EDGAR | +0.00% | -4.54% | |
| Form 8-K OnKure Therapeutics, For: Nov 06 | SEC filing · Form 8-K | SEC EDGAR | +0.00% | -4.54% | |
| Form POS AM OnKure Therapeutics, | SEC filing · Form POS | SEC EDGAR | +0.00% | -4.54% | |
| Form S-3 OnKure Therapeutics, | SEC filing · Form S-3 | SEC EDGAR | +0.00% | -4.54% | |
| OnKure Therapeutics Reports Third Quarter 2025 Financial Results and Provides a Business Update | Press release | GlobeNewswire | +0.00% | -4.54% | |
| OnKure Therapeutics to Participate in Upcoming Investor Conferences | Press release | GlobeNewswire | +0.00% | -3.54% | |
| Form 10-Q OnKure Therapeutics, For: Jun 30 | SEC filing · Form 10-Q | SEC EDGAR | +1.12% | +9.59% | |
| Form 8-K OnKure Therapeutics, For: Aug 12 | SEC filing · Form 8-K | SEC EDGAR | +1.12% | +9.59% | |
| OnKure Therapeutics Reports Second Quarter 2025 Financial Results and Provides a Business Update | Press release | GlobeNewswire | +1.12% | +9.59% | |
| Form 8-K OnKure Therapeutics, For: Jun 26 | SEC filing · Form 8-K | SEC EDGAR | +3.27% | -2.04% | |
| Form 8-K OnKure Therapeutics, For: May 27 | SEC filing · Form 8-K | SEC EDGAR | +4.30% | +4.51% | |
| Form 10-Q OnKure Therapeutics, For: Mar 31 | SEC filing · Form 10-Q | SEC EDGAR | -3.20% | -10.80% | |
| Form 8-K OnKure Therapeutics, For: May 06 | SEC filing · Form 8-K | SEC EDGAR | -3.20% | -10.80% | |
| OnKure Therapeutics Reports First Quarter 2025 Financial Results and Business Highlights | Press release | GlobeNewswire | -3.20% | -10.80% | |
| Form ARS OnKure Therapeutics, For: Dec 31 | SEC filing · Form ARS | SEC EDGAR | -3.39% | -2.03% | |
| Form DEF 14A OnKure Therapeutics, For: May 27 | SEC filing · Form DEF | SEC EDGAR | -3.39% | -2.03% | |
| Form DEFA14A OnKure Therapeutics, | SEC filing · Form DEFA14A | SEC EDGAR | -3.39% | -2.03% | |
| Form EFFECT OnKure Therapeutics, | SEC filing · Form EFFECT | SEC EDGAR | -0.98% | -2.75% | |
| Form POS AM OnKure Therapeutics, | SEC filing · Form POS | SEC EDGAR | -1.84% | +3.06% | |
| Form 10-K OnKure Therapeutics, For: Dec 31 | SEC filing · Form 10-K | SEC EDGAR | +0.00% | -5.71% | |
| Form 8-K OnKure Therapeutics, For: Mar 10 | SEC filing · Form 8-K | SEC EDGAR | +0.00% | -5.71% | |
| Form S-8 OnKure Therapeutics, | SEC filing · Form S-8 | SEC EDGAR | +0.00% | -5.71% | |
| OnKure Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business Highlights | Press release | GlobeNewswire | +0.00% | -5.71% | |
| OnKure Therapeutics to Present at Upcoming Leerink and Stifel Investor Conferences | Press release | GlobeNewswire | -1.43% | +6.13% | |
| Form 8-K OnKure Therapeutics, For: Dec 10 | SEC filing · Form 8-K | SEC EDGAR | +3.13% | -0.22% | |
| OnKure Announces Encouraging Preliminary Safety, Tolerability, and Pharmacokinetic (PK) Data from its First-In-Human PIKture-01 Trial of OKI-219 | Press release | GlobeNewswire | +3.13% | -0.22% | |
| Form S-8 OnKure Therapeutics, | SEC filing · Form S-8 | SEC EDGAR | +3.13% | -0.22% |
Each reaction is the move the market actually made, measured from the news timestamp. Headlines link through to the OKUR section they belong to.
Where else OKUR is measured.
OKUR earnings → · Analyst actions → · SEC filings →
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Every name we’ve measured, in one place.
How the numbers are made.
How is OnKure Therapeutics, Inc. - Class A's median reaction calculated?
Every labeled OKUR news event is measured from its own timestamp: the last trade before the news is the base price, and the move is read at fixed horizons — 30 minutes of trading, then the close. The median across 194 events is what this page reports. Point-in-time, zero look-ahead: no event borrows information from a later one.
What counts as a positive reaction?
Any event whose price move is above zero at the horizon, relative to the last trade before the news timestamp. 37% of OKUR's measured events are up at 30 minutes; the rest close the window flat or negative.
How often is this page updated?
The news table refreshes automatically as new events are labeled and priced. The reaction medians are re-pulled in batches from the dataset — the figures here are as of 2026-09-21.
Does OKUR's past reaction predict its next one?
No. These are realized facts about past events, not forecasts. They describe a distribution — they say nothing certain about any future move.