NuCana plc - American Depositary Shares (NCNA)
NCNA moved a median of -1.28% 30 minutes after news, and -1.09% by the close. How NCNA actually reacts to news — the realized, point-in-time move the market made, measured across 171 labeled events over the last three years with zero look-ahead.
NCNA’s median reaction, across the day.
| Horizon | Median | % positive | Events |
|---|---|---|---|
| 5-min | 0.00% | 31% | 167 |
| 30-min | -1.28% | 40% | 171 |
| 60-min | -0.94% | 37% | 171 |
| to close | -1.09% | 38% | 171 |
| Middle 50% of NCNA reactions | -3.73% to +1.82% |
|---|---|
| Median reaction (30-min) | -1.28% |
| Measured reactions | 171 |
Half of all NuCana plc - American Depositary Shares news events land between -3.73% and +1.82% at 30 minutes.
Reaction stats as of 2026-09-21. Newest measured event . Reaction = percent move vs. the price at the news timestamp.
Email me when NCNA moves on news.
One email per qualifying move — the headline, the measured reaction, and how it compares to NCNA's baseline. Nothing else.
Recent NCNA events, each with its measured reaction.
| Date | Headline | Event | Source | 5-min | To close |
|---|---|---|---|---|---|
| Form 6-K NuCana plc For: Sep 30 | SEC filing · Form 6-K | SEC EDGAR | +1.55% | +4.65% | |
| Form 6-K NuCana plc For: Jun 30 | SEC filing · Form 6-K | SEC EDGAR | +4.03% | +6.71% | |
| Form 6-K NuCana plc For: Jun 08 | SEC filing · Form 6-K | SEC EDGAR | +0.00% | +4.59% | |
| Form 6-K NuCana plc For: Jun 01 | SEC filing · Form 6-K | SEC EDGAR | +0.00% | -3.56% | |
| Form 6-K NuCana plc For: May 14 | SEC filing · Form 6-K | SEC EDGAR | +1.97% | +7.39% | |
| Form 6-K NuCana plc For: May 06 | SEC filing · Form 6-K | SEC EDGAR | — | -3.24% | |
| Form 20-F NuCana plc For: Dec 31 | SEC filing · Form 20-F | SEC EDGAR | -0.88% | -2.94% | |
| Form 6-K NuCana plc For: Mar 19 | SEC filing · Form 6-K | SEC EDGAR | -0.88% | -2.94% | |
| Form S-8 NuCana plc | SEC filing · Form S-8 | SEC EDGAR | -0.88% | -2.94% | |
| Form 6-K NuCana plc For: Jan 06 | SEC filing · Form 6-K | SEC EDGAR | — | +1.09% | |
| Form 6-K NuCana plc For: Dec 17 | SEC filing · Form 6-K | SEC EDGAR | -0.85% | -2.83% | |
| Form 6-K NuCana plc For: Dec 10 | SEC filing · Form 6-K | SEC EDGAR | -3.37% | -4.04% | |
| Form 6-K NuCana plc For: Nov 05 | SEC filing · Form 6-K | SEC EDGAR | +1.31% | -0.52% | |
| Form 6-K NuCana plc For: Oct 20 | SEC filing · Form 6-K | SEC EDGAR | -0.95% | -5.15% | |
| Form 6-K NuCana plc For: Oct 14 | SEC filing · Form 6-K | SEC EDGAR | -2.88% | +2.63% | |
| DNA Synthesis Inhibitors Market Gains Momentum with Growing Adoption in Oncology and Virology | DelveInsight | Press release | PR Newswire | -0.74% | +20.21% | |
| Form 6-K NuCana plc For: Sep 05 | SEC filing · Form 6-K | SEC EDGAR | +1.39% | -0.35% | |
| Form 6-K NuCana plc For: Sep 03 | SEC filing · Form 6-K | SEC EDGAR | -0.17% | +0.33% | |
| NuCana to Present Data on NUC-7738’s Synergy with PD-1 Inhibitors at the ESMO Congress 2025 | Press release | GlobeNewswire | -0.17% | +0.33% | |
| Form 6-K NuCana plc For: Jun 30 | SEC filing · Form 6-K | SEC EDGAR | -2.40% | -0.60% | |
| Form 6-K NuCana plc For: Aug 01 | SEC filing · Form 6-K | SEC EDGAR | -7.14% | -1.08% | |
| Form 6-K NuCana plc For: Jul 21 | SEC filing · Form 6-K | SEC EDGAR | -1.87% | -4.67% | |
| Form 6-K NuCana plc For: Jul 11 | SEC filing · Form 6-K | SEC EDGAR | -2.34% | -9.71% | |
| Form 6-K NuCana plc For: Jul 09 | SEC filing · Form 6-K | SEC EDGAR | -3.40% | -26.73% | |
| Form 6-K NuCana plc For: Jun 30 | SEC filing · Form 6-K | SEC EDGAR | -5.89% | -21.37% | |
| Form 6-K NuCana plc For: Jun 27 | SEC filing · Form 6-K | SEC EDGAR | -5.89% | -21.37% | |
| Form EFFECT NuCana plc | SEC filing · Form EFFECT | SEC EDGAR | +1.99% | -2.21% | |
| Form 6-K NuCana plc For: Jun 20 | SEC filing · Form 6-K | SEC EDGAR | +4.94% | -1.22% | |
| Form 6-K NuCana plc For: Jun 18 | SEC filing · Form 6-K | SEC EDGAR | +0.15% | -7.49% | |
| Form F-3/A NuCana plc | SEC filing · Form F-3 | SEC EDGAR | +0.00% | -6.00% | |
| Form 6-K NuCana plc For: Jun 05 | SEC filing · Form 6-K | SEC EDGAR | +6.87% | +12.39% | |
| Form 6-K NuCana plc For: Jun 02 | SEC filing · Form 6-K | SEC EDGAR | -5.49% | +36.84% | |
| Form EFFECT NuCana plc | SEC filing · Form EFFECT | SEC EDGAR | +1.91% | +5.51% | |
| Form F-1/A NuCana plc | SEC filing · Form F-1 | SEC EDGAR | +0.00% | -11.52% | |
| Form F-1/A NuCana plc | SEC filing · Form F-1 | SEC EDGAR | +0.00% | -1.83% | |
| Form F-1 NuCana plc | SEC filing · Form F-1 | SEC EDGAR | -4.38% | -19.36% | |
| Form 6-K NuCana plc For: Apr 23 | SEC filing · Form 6-K | SEC EDGAR | -4.38% | -19.36% | |
| Terray Therapeutics Appoints Elliott Levy, MD, to Scientific Advisory Board | Press release | Business Wire | -2.57% | -5.87% | |
| Form 20-F NuCana plc For: Dec 31 | SEC filing · Form 20-F | SEC EDGAR | +0.00% | -1.41% | |
| Form 6-K NuCana plc For: Mar 20 | SEC filing · Form 6-K | SEC EDGAR | +0.00% | -1.41% | |
| Form 6-K NuCana plc For: Mar 18 | SEC filing · Form 6-K | SEC EDGAR | +0.00% | +1.37% | |
| Aurion Biotech Appoints Donald Munoz as Chief Financial Officer | Press release | Business Wire | -0.88% | -1.63% | |
| Form 6-K NuCana plc For: Feb 10 | SEC filing · Form 6-K | SEC EDGAR | -0.88% | -1.63% | |
| Form 6-K NuCana plc For: Nov 25 | SEC filing · Form 6-K | SEC EDGAR | -1.54% | -3.08% | |
| Form 6-K NuCana plc For: Nov 12 | SEC filing · Form 6-K | SEC EDGAR | +0.65% | +3.90% | |
| Form 6-K NuCana plc For: Sep 30 | SEC filing · Form 6-K | SEC EDGAR | -1.80% | -7.21% | |
| Form 6-K NuCana plc For: Sep 26 | SEC filing · Form 6-K | SEC EDGAR | -7.46% | -24.03% | |
| Form 6-K NuCana plc For: Sep 16 | SEC filing · Form 6-K | SEC EDGAR | -1.24% | -0.93% | |
| Form 6-K NuCana plc For: Aug 29 | SEC filing · Form 6-K | SEC EDGAR | +13.06% | +3.98% | |
| Form 6-K NuCana plc For: Jun 30 | SEC filing · Form 6-K | SEC EDGAR | -12.32% | +0.29% |
Each reaction is the move the market actually made, measured from the news timestamp. Headlines link through to the NCNA section they belong to.
Where else NCNA is measured.
NCNA earnings → · Analyst actions → · SEC filings →
Other Healthcare names, measured the same way
| Ticker | Events | Median 30-min | % positive |
|---|---|---|---|
| Aytu BioPharma, Inc. (AYTU) | 172 | -0.14% | 40% |
| Alpine Immune Sciences, Inc. (ALPN) | 171 | +0.05% | 54% |
| UCB SA NPV (UCBJF) | 171 | 0.00% | 3% |
| ESSILOR LXTTCA UNSP/ADR (ESLOY) | 169 | -0.01% | 45% |
Same sector, same measurement: percent move vs. the price at the news timestamp, read at 30 minutes. Sample sizes differ, so the medians are comparable but the confidence behind them is not.
All Healthcare names, measured the same way →
Every ticker we measure the same way24
Apple (AAPL)
How AAPL actually reacts to news, measured.
NVIDIA (NVDA)
How NVDA actually reacts to news, measured.
Tesla (TSLA)
How TSLA actually reacts to news, measured.
Microsoft (MSFT)
How MSFT actually reacts to news, measured.
Advanced Micro Devices (AMD)
How AMD actually reacts to news, measured.
Amazon (AMZN)
How AMZN actually reacts to news, measured.
Alphabet (GOOG)
How GOOG actually reacts to news, measured.
Meta Platforms (META)
How META actually reacts to news, measured.
Broadcom (AVGO)
How AVGO actually reacts to news, measured.
JPMorgan Chase (JPM)
How JPM actually reacts to news, measured.
Visa (V)
How V actually reacts to news, measured.
Walmart (WMT)
How WMT actually reacts to news, measured.
Eli Lilly (LLY)
How LLY actually reacts to news, measured.
UnitedHealth Group (UNH)
How UNH actually reacts to news, measured.
Netflix (NFLX)
How NFLX actually reacts to news, measured.
Johnson & Johnson (JNJ)
How JNJ actually reacts to news, measured.
Exxon Mobil (XOM)
How XOM actually reacts to news, measured.
Home Depot (HD)
How HD actually reacts to news, measured.
Costco (COST)
How COST actually reacts to news, measured.
Mastercard (MA)
How MA actually reacts to news, measured.
Oracle (ORCL)
How ORCL actually reacts to news, measured.
Salesforce (CRM)
How CRM actually reacts to news, measured.
Bank of America (BAC)
How BAC actually reacts to news, measured.
Coca-Cola (KO)
How KO actually reacts to news, measured.
Walt Disney (DIS)
How DIS actually reacts to news, measured.
Browse all tickers
Every name we’ve measured, in one place.
How the numbers are made.
How is NuCana plc - American Depositary Shares's median reaction calculated?
Every labeled NCNA news event is measured from its own timestamp: the last trade before the news is the base price, and the move is read at fixed horizons — 30 minutes of trading, then the close. The median across 171 events is what this page reports. Point-in-time, zero look-ahead: no event borrows information from a later one.
What counts as a positive reaction?
Any event whose price move is above zero at the horizon, relative to the last trade before the news timestamp. 40% of NCNA's measured events are up at 30 minutes; the rest close the window flat or negative.
How often is this page updated?
The news table refreshes automatically as new events are labeled and priced. The reaction medians are re-pulled in batches from the dataset — the figures here are as of 2026-09-21.
Does NCNA's past reaction predict its next one?
No. These are realized facts about past events, not forecasts. They describe a distribution — they say nothing certain about any future move.