ProShares UltraShort Nasdaq Biotechnology (BIS)
BIS moved a median of +0.04% 30 minutes after news, and +0.51% by the close. How BIS actually reacts to news — the realized, point-in-time move the market made, measured across 724 labeled events over the last three years with zero look-ahead.
BIS’s median reaction, across the day.
| Horizon | Median | % positive | Events |
|---|---|---|---|
| 5-min | +0.17% | 51% | 284 |
| 30-min | +0.04% | 50% | 379 |
| 60-min | +0.55% | 89% | 575 |
| to close | +0.51% | 76% | 724 |
| Middle 50% of BIS reactions | -0.07% to +0.81% |
|---|---|
| Median reaction (30-min) | +0.04% |
| Measured reactions | 724 |
Half of all ProShares UltraShort Nasdaq Biotechnology news events land between -0.07% and +0.81% at 30 minutes.
Reaction stats as of 2026-09-21. Newest measured event . Reaction = percent move vs. the price at the news timestamp.
Email me when BIS moves on news.
One email per qualifying move — the headline, the measured reaction, and how it compares to BIS's baseline. Nothing else.
Recent BIS events, each with its measured reaction.
| Date | Headline | Event | Source | 5-min | To close |
|---|---|---|---|---|---|
| ProShares Announces ETF Share Splits | Press release | Business Wire | — | -1.65% | |
| Form 485BXT PROSHARES TRUST | SEC filing · Form 485BXT | SEC EDGAR | +0.00% | +1.18% | |
| Form CERT PROSHARES TRUST | SEC filing · Form CERT | SEC EDGAR | +0.07% | -0.40% | |
| Form 485BPOS PROSHARES TRUST | SEC filing · Form 485BPOS | SEC EDGAR | -0.89% | -0.62% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | — | +3.03% | |
| Form 497J PROSHARES TRUST | SEC filing · Form 497J | SEC EDGAR | +0.28% | +0.28% | |
| Form 497K PROSHARES TRUST | SEC filing · Form 497K | SEC EDGAR | — | +0.00% | |
| Form 8-A12B PROSHARES TRUST | SEC filing · Form 8-A12B | SEC EDGAR | — | +3.03% | |
| Form N-PX PROSHARES TRUST For: Jun 30 | SEC filing · Form N-PX | SEC EDGAR | — | +3.03% | |
| Form 485BXT PROSHARES TRUST | SEC filing · Form 485BXT | SEC EDGAR | — | +1.69% | |
| Form 24F-2NT PROSHARES TRUST For: May 31 | SEC filing · Form 24F-2NT | SEC EDGAR | — | -0.14% | |
| Form N-CEN PROSHARES TRUST For: May 31 | SEC filing · Form N-CEN | SEC EDGAR | +0.00% | -0.77% | |
| Form N-CSR PROSHARES TRUST For: May 31 | SEC filing · Form N-CSR | SEC EDGAR | — | -1.03% | |
| Form NPORT-P PROSHARES TRUST For: May 31 | SEC filing · Form NPORT-P | SEC EDGAR | — | -0.21% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | +1.41% | +1.76% | |
| Form 485APOS PROSHARES TRUST | SEC filing · Form 485APOS | SEC EDGAR | -0.97% | +0.55% | |
| Form 485APOS PROSHARES TRUST | SEC filing · Form 485APOS | SEC EDGAR | -0.97% | +0.14% | |
| Form 485APOS PROSHARES TRUST | SEC filing · Form 485APOS | SEC EDGAR | -0.79% | -2.31% | |
| Form 485BPOS PROSHARES TRUST | SEC filing · Form 485BPOS | SEC EDGAR | +1.24% | +1.24% | |
| Form 497J PROSHARES TRUST | SEC filing · Form 497J | SEC EDGAR | +1.24% | +1.24% | |
| Form 497K PROSHARES TRUST | SEC filing · Form 497K | SEC EDGAR | +1.24% | +1.24% | |
| Form 8-A12B PROSHARES TRUST | SEC filing · Form 8-A12B | SEC EDGAR | +1.24% | +1.24% | |
| Form CERT PROSHARES TRUST | SEC filing · Form CERT | SEC EDGAR | +1.24% | +1.24% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | — | +0.41% | |
| Form NPORT-P PROSHARES TRUST For: Feb 29 | SEC filing · Form NPORT-P | SEC EDGAR | — | +0.51% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | +0.96% | +0.64% | |
| Form 497K PROSHARES TRUST | SEC filing · Form 497K | SEC EDGAR | +0.96% | +0.64% | |
| Form 485APOS PROSHARES TRUST | SEC filing · Form 485APOS | SEC EDGAR | — | +0.27% | |
| Form 485BPOS PROSHARES TRUST | SEC filing · Form 485BPOS | SEC EDGAR | — | +0.27% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | — | +3.35% | |
| Form 485BPOS PROSHARES TRUST | SEC filing · Form 485BPOS | SEC EDGAR | — | +2.91% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | — | +2.91% | |
| Form 497J PROSHARES TRUST | SEC filing · Form 497J | SEC EDGAR | — | +2.91% | |
| Form 497K PROSHARES TRUST | SEC filing · Form 497K | SEC EDGAR | — | +2.91% | |
| Form 8-A12B PROSHARES TRUST | SEC filing · Form 8-A12B | SEC EDGAR | — | +2.91% | |
| Form CERT PROSHARES TRUST | SEC filing · Form CERT | SEC EDGAR | — | +2.91% | |
| Form CERT PROSHARES TRUST | SEC filing · Form CERT | SEC EDGAR | — | -0.30% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | — | -0.28% | |
| Form 497K PROSHARES TRUST | SEC filing · Form 497K | SEC EDGAR | — | -0.28% | |
| Form 485BPOS PROSHARES TRUST | SEC filing · Form 485BPOS | SEC EDGAR | — | +0.00% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | — | -0.28% | |
| Form 497J PROSHARES TRUST | SEC filing · Form 497J | SEC EDGAR | — | +0.00% | |
| Form 497K PROSHARES TRUST | SEC filing · Form 497K | SEC EDGAR | — | +0.00% | |
| Form 8-A12B PROSHARES TRUST | SEC filing · Form 8-A12B | SEC EDGAR | — | -0.28% | |
| Form 485BXT PROSHARES TRUST | SEC filing · Form 485BXT | SEC EDGAR | — | +0.98% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | +0.00% | -3.03% | |
| Form 485BXT PROSHARES TRUST | SEC filing · Form 485BXT | SEC EDGAR | -0.61% | -2.63% | |
| Form 485BXT PROSHARES TRUST | SEC filing · Form 485BXT | SEC EDGAR | — | -1.03% | |
| Form N-CSRS PROSHARES TRUST For: Nov 30 | SEC filing · Form N-CSRS | SEC EDGAR | — | -0.61% | |
| Form 497 PROSHARES TRUST | SEC filing · Form 497 | SEC EDGAR | +0.00% | +0.17% |
Each reaction is the move the market actually made, measured from the news timestamp. Headlines link through to the BIS section they belong to.
Where else BIS is measured.
BIS earnings → · Analyst actions → · SEC filings →
Every ticker we measure the same way24
Apple (AAPL)
How AAPL actually reacts to news, measured.
NVIDIA (NVDA)
How NVDA actually reacts to news, measured.
Tesla (TSLA)
How TSLA actually reacts to news, measured.
Microsoft (MSFT)
How MSFT actually reacts to news, measured.
Advanced Micro Devices (AMD)
How AMD actually reacts to news, measured.
Amazon (AMZN)
How AMZN actually reacts to news, measured.
Alphabet (GOOG)
How GOOG actually reacts to news, measured.
Meta Platforms (META)
How META actually reacts to news, measured.
Broadcom (AVGO)
How AVGO actually reacts to news, measured.
JPMorgan Chase (JPM)
How JPM actually reacts to news, measured.
Visa (V)
How V actually reacts to news, measured.
Walmart (WMT)
How WMT actually reacts to news, measured.
Eli Lilly (LLY)
How LLY actually reacts to news, measured.
UnitedHealth Group (UNH)
How UNH actually reacts to news, measured.
Netflix (NFLX)
How NFLX actually reacts to news, measured.
Johnson & Johnson (JNJ)
How JNJ actually reacts to news, measured.
Exxon Mobil (XOM)
How XOM actually reacts to news, measured.
Home Depot (HD)
How HD actually reacts to news, measured.
Costco (COST)
How COST actually reacts to news, measured.
Mastercard (MA)
How MA actually reacts to news, measured.
Oracle (ORCL)
How ORCL actually reacts to news, measured.
Salesforce (CRM)
How CRM actually reacts to news, measured.
Bank of America (BAC)
How BAC actually reacts to news, measured.
Coca-Cola (KO)
How KO actually reacts to news, measured.
Walt Disney (DIS)
How DIS actually reacts to news, measured.
Browse all tickers
Every name we’ve measured, in one place.
How the numbers are made.
How is ProShares UltraShort Nasdaq Biotechnology's median reaction calculated?
Every labeled BIS news event is measured from its own timestamp: the last trade before the news is the base price, and the move is read at fixed horizons — 30 minutes of trading, then the close. The median across 724 events is what this page reports. Point-in-time, zero look-ahead: no event borrows information from a later one.
What counts as a positive reaction?
Any event whose price move is above zero at the horizon, relative to the last trade before the news timestamp. 50% of BIS's measured events are up at 30 minutes; the rest close the window flat or negative.
How often is this page updated?
The news table refreshes automatically as new events are labeled and priced. The reaction medians are re-pulled in batches from the dataset — the figures here are as of 2026-09-21.
Does BIS's past reaction predict its next one?
No. These are realized facts about past events, not forecasts. They describe a distribution — they say nothing certain about any future move.