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Stock impact report

Zentalis Pharmaceuticals to Present Preclinical Azenosertib Data at ESMO 2024

Zentalis Pharmaceuticals, Inc. - common stock (ZNTL) 
Company Research Source: GlobeNewswire
SAN DIEGO, Sept. 09, 2024 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical-stage biopharmaceutical company discovering and developing clinically differentiated small molecule therapeutics targeting fundamental biological pathways of cancers, today announced that the company will present preclinical data from its selective WEE1 inhibitor azenosertib at the European Society of Medical Oncology (ESMO) 2024 Congress, occurring September 13-17 in Barcelona, Spain. “The confluence of DNA damage induced by TOP1 inhibitors and cell cycle deregulation and genomic instability induced by azenosertib provides a mechanistic rationale for this combination, as well as more broadly with antibody drug conjugates (ADCs) utilizing these inhibitors as payloads,” said Mark Lackner, PhD, Chief Scientific Officer. “The preclinical data demonstrated this synergistic effect and suggest that azenosertib in combination with ADCs could be an important therapeutic approach in Show less Read more
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