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-0.00268115942028983 -0.00724637681159426 0 0 0.0197101449275362 0.0169082125603863 -0.00966183574879228 -0.00241545893719802
Stock impact report

FDA lifts partial clinical hold on Zentalis Pharma's cancer WEE1 inhibitor [Yahoo! Finance]

Zentalis Pharmaceuticals, Inc. - common stock (ZNTL) 
Company Research Source: Yahoo! Finance
Zentalis Pharmaceuticals' azenosertib, allowing the company to continue evaluating the drug as a treatment for cancer. Following the FDA decision, Zentalis' stock was up by 53%, from $3.24 at closing on 13 September to $4.96 at the market opening on 16 September. In an announcement, Zentalis's CEO Kimberly Blackwell said: “Our confidence in the therapeutic index of azenosertib has been unwavering, and we continue to believe in the potential for this treatment to address unmet medical needs faced by people living with gynecologic malignancies.” The FDA placed the partial hold on three studies investigating azenosertib in June 2024 following the death of two trial participants. Azenosertib was being investigated in solid tumours in a Phase I study (NCT04158336) and more specifically in patients with ovarian (NCT05128825) and uterine cancer (NCT04814108) in two Phase II studies. Two patients in the ovarian cancer study died due to presumed blood-related infection associated with th Show less Read more
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