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Stock impact report

WVE Stock Soars on Upbeat Efficacy Data From Muscle Disease Study [Yahoo! Finance]

Wave Life Sciences Ltd. - Ordinary Shares (WVE) 
Last wave life sciences ltd. - ordinary shares earnings: 3/2 06:45 am Check Earnings Report
Company Research Source: Yahoo! Finance
Shares of Wave Life Sciences WVE surged 53.4% on Tuesday after the company announced positive interim data from a mid-stage study evaluating its investigational candidate, WVE-N531, to treat boys with Duchenne muscular dystrophy (DMD) who are amenable to exon 53 skipping. WVE-N531, an exon skipping oligonucleotide, is currently being developed as a disease-modifying treatment for DMD indication in boys. The candidate enjoys the FDA's Orphan Drug and Rare Pediatric Disease designations in the United States for the same indication. The data readout is from the planned interim analysis of the phase II FORWARD-53 study after 24 weeks, where the DMD patients received a 10 mg/kg dose of WVE-N531 every two weeks. Per Wave Life Sciences, treatment with the candidate demonstrated substantial dystrophin expression and was generally safe and overall well tolerated. WVE expects to share 48-week data from the complete FORWARD-53 study of WVE-N531 for DMD in the first quarter of 2025 and rec Show less Read more
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