Exclusive: Holoclara raises $16 million Series A to develop therapeutics—with worms [Fortune]
Wells Fargo & Company (WFC)
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Source: Fortune
If you're wondering why all the fuss, the answer's pretty simple: In the scientific sense, worms are rather special. “It's the one organism that I would say is the simplest, that we know the most about, and that's why you've seen so many Nobel Prizes from C. elegans [roundworms],” said Choe. “You know everything about it, from when it goes from one cell, to two, to four to the entire organism.” Worms have co-evolved with humans for millions of years. Now, there's mounting evidence that worms hold potential as therapeutic agents, as suggested by cases where exposure to worms has, for example, alleviated conditions like asthma “You can develop tools within this organism,” said Choe. “Don't forget, you lay it flat on a microscope, on a thin sheet of agar, with a tiny drop of anesthetic and it'll just go to sleep on its side—you can then zap with a laser any single cell or neuron you want.” So, that's what Holoclara is chasing—that for even debilitating allergies and autoimmune d
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