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Stock impact report

Voyager Selects Tau Silencing Gene Therapy Development Candidate for Alzheimer's Disease [Yahoo! Finance]

Voyager Therapeutics, Inc. (VYGR) 
Last voyager therapeutics, inc. earnings: 3/3 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.voyagertherapeutics.com
Company Research Source: Yahoo! Finance
- VY1706 is the fifth neuro gene therapy development candidate nominated leveraging Voyager's IV-delivered, CNS-penetrant TRACER capsids - LEXINGTON, Mass., Nov. 20, 2024 (GLOBE NEWSWIRE) -- Voyager Therapeutics, Inc. (Nasdaq: VYGR), a biotechnology company dedicated to advancing neurogenetic medicines, today announced that it has selected a lead development candidate, VY1706, for its tau silencing gene therapy program in Alzheimer's disease. The Company anticipates filing an investigational new drug (IND) application with the U.S. Food and Drug Administration and a clinical trial application (CTA) with Health Canada for VY1706 in 2026. VY1706 combines a potent siRNA construct to decrease the expression of tau with an IV-delivered, blood-brain barrier-penetrant TRACER™ capsid. In a non-human primate (NHP) study, a single dose of VY1706 resulted in reductions in tau mRNA levels of 50% to 73% across the cerebral cortex, including in areas of the brain where tau accumulates during p Show less Read more
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