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0.0263157894736841 0.0210526315789474 0.121052631578947 0.11578947368421 -0.0115789473684211 -0.0263157894736842 -0.0105263157894737 -0.0947368421052632
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vTv Therapeutics Announces Positive Topline Results from Part 1 of the Phase 2 Simplici-T1 Trial in Patients with Type 1 Diabetes

vTv Therapeutics Inc. - Class A (VTVT) 
Last vtv therapeutics inc. - class a earnings: 7/31 04:30 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.vtvtherapeutics.com
Company Research Source: Business Wire
TTP399, a novel glucokinase activator shows statistically significant reduction in HbA1c without increases in ketones or hypoglycemia HIGH POINT, N.C.--(BUSINESS WIRE)-- vTv Therapeutics Inc. (Nasdaq: VTVT) today announced positive results from the primary analysis of Part 1 of the Phase 2 Simplici-T1 trial assessing the liver-selective glucokinase activator TTP399 in adult patients with type 1 diabetes (T1D). In this double-blind, placebo-controlled 12-week trial, the baseline mean HbA1c for the groups treated with TTP399 and placebo was 7.3% and 7.4%, respectively. Patients treated with TTP399 (n=8) showed a statistically significant mean reduction in HbA1c of 0.6% at 12 weeks, while the group treated with placebo (n=11) showed a mean increase in HbA1c of 0.1%, resulting in a mean difference of 0.7% in the TTP399 group relative to the placebo group (p=0.03). At the same time, trends toward Show less Read more
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