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-0.000999052181263894 -0.00138330302021165 -0.00358634116351148 -0.00146015318800111 0.00505930271281098 0.00668596459768941 0.0193790506442606 0.0238491687373518
Stock impact report

Vertex's stock hurt after non-opioid pain drug shows benefit similar to placebo [Yahoo! Finance]

Vertex Pharmaceuticals Incorporated (VRTX) 
Last vertex pharmaceuticals incorporated earnings: 4/29 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.vrtx.com
Company Research Source: Yahoo! Finance
with painful lumbosacral radiculopathy (LSR) but is not too dissimilar to placebo. The trial (NCT06176196), evaluating suzetrigine, an investigational, oral, highly selective NaV1.8 pain signal inhibitor met its primary endpoint with a statistically significant and clinically meaningful reduction in pain on the numeric pain rating scale (NPRS). The 11-point scale ranges from 0 (no pain) to 10 (worst pain imaginable). The suzetrigine arm showed a statistically significant and clinically meaningful within-group reduction from baseline in pain with a mean change in NPRS of -2.02. The placebo arm was only 0.04 points worse, with a mean change in NPRS of -1.98. Vertex clarified that the study was not designed nor powered for statistical comparison between suzetrigine and placebo. Investors were not convinced by Vertex's bullish outlook on its data, with the company's stock falling by 15.53% compared to market close yesterday (18 December). Vertex also conducted post-hoc analyses to Show less Read more
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