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-0.000488956158128218 0.000641338087786357 0.00130832969908415 0.00301428901259591 0.00406608347656545 0.0149816577306894 0.0174572227495447 0.0227290218311484
Stock impact report

Vertex's $10 Billion Blow: Painkiller Trial Results Spark Investor Panic [Yahoo! Finance]

Vertex Pharmaceuticals Incorporated (VRTX) 
Last vertex pharmaceuticals incorporated earnings: 4/29 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.vrtx.com
Company Research Source: Yahoo! Finance
The biotech heavyweight's much-anticipated non-opioid painkiller, suzetrigine, flopped in its latest Phase 2 trial for chronic lower back pain. The results? Pain scores for patients on suzetrigine barely edged out those on a placebo, with a reduction of 2.02 vs. 1.98 on a standard pain scale. That tiny margin wasn't enough to impress Wall Streetor investors. Shares nosedived 14% on Thursday, wiping out more than $10 billion in market value. Ouch. Warning! GuruFocus has detected 5 Warning Signs with VRTX. Here's the kicker: Vertex isn't giving up. They're pressing ahead with a Phase 3 trial, banking on tweaks to trial designs to tackle what they're calling a placebo response problem. Some analysts remain hopeful, but plenty aren't buying it. RBC Capital Markets went as far as calling this a near worst-case scenario for the drug's potential in chronic pain. Still, the FDA is reviewing suzetrigine for acute pain with a decision due by January 30, 2025so there's a glimmer of hope for Show less Read more
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