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-0.00150375939849621 0 -0.00300751879699255 -0.00526315789473686 -0.00526315789473686 -0.0124060150375941 -0.0210526315789473 -0.0225563909774437
Stock impact report

Viridian (VRDN) Up 10% on Clinical Updates for Eye Disease Drug [Yahoo! Finance]

Viridian Therapeutics, Inc. (VRDN) 
Company Research Source: Yahoo! Finance
This August, management intends to start two late-stage studies, namely REVEAL-1 and REVEAL-2, evaluating two active dosing regimens of VRDN-003 in active and chronic TED, respectively. In both studies, patients will initially receive a high initial dose of 600mg (split into two 300mg injections). Following this dosage, patients will continue with injections of 300mg each. The total number of injections will depend on the treatment regimen – six injections in the four-week regimen and three injections in the eight-week regimen. The primary endpoint of each study will be the proptosis responder rate (at least 2mm improvement in proptosis from baseline) after 24 weeks of treatment. Post this period, the study patients will be followed for another 28 weeks. Viridian intends to enroll around 84 and 126 patients in the REVEAL-1 and REVEAL-2 studies, respectively. Viridian expects to report top-line data from both clinical studies in the first half of 2026. If data from the studies are Show less Read more
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