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0 0.000549752611324794 -0.00219901044529957 -0.00274876305662456 -0.00219901044529957 -0.00384826827927434 -0.00494777350192413 0.013221550302364
Stock impact report

Viridian Therapeutics' stock jumps after Phase III trial met all endpoints [Yahoo! Finance]

Viridian Therapeutics, Inc. (VRDN) 
Company Research Source: Yahoo! Finance
Previously known as VRDN-001, veligrotug won in the Phase III THRIVE trial (NCT05176639). It also boasted positive safety data in patients with TED, which is also known as Graves' disease. The news saw the Massachusetts-based company's stock price rise by 32% on 10 September, having closed at $14.19 on 9 September and $18.75 on 10 September. The trial met the primary and all secondary endpoints at 15 weeks after five infusions of veligrotug, showing highly statistically significant improvements in all the measured signs and symptoms of TED. Veligrotug additionally showed a rapid onset of action, with more than half of veligrotug-treated patients achieving a proptosis response after just one infusion. After 15 weeks, the treatment group saw a 70% proptosis responder rate (PRR) compared to 5% in the placebo arm. There was a 2.9mm mean reduction in proptosis from baseline in patients receiving veligrotug, compared with a 0.5mm reduction in patients receiving a placebo. Patients Show less Read more
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