Vanda Pharmaceuticals Announces Orphan Drug Designation Granted for VGT-1849A, a Novel and Selective Antisense Oligonucleotide Candidate for the Treatment of Polycythemia Vera [Yahoo! Fina...
Vanda Pharmaceuticals Inc. (VNDA)
Last vanda pharmaceuticals inc. earnings: 2/25 04:01 pm
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Source: Yahoo! Finance
Food and Drug Administration (FDA) has granted Orphan Drug Designation for VGT-1849A, a selective antisense oligonucleotide (ASO)-based JAK2 inhibitor for the treatment of polycythemia vera (PV), a form of a rare hematologic malignancy that is estimated to affect 1 in 2000 Americans. Vanda Logo (PRNewsfoto/Vanda Pharmaceuticals Inc.) PV is a chronic myeloproliferative disorder characterized by aberrant hematopoiesis of myeloid lineage with exuberant red cell production and increased release of pro-inflammatory cytokines. More than 95% of PV patients harbor the JAK2 V617F gain-of-function mutation leading to aberrant JAK2 production. Inhibiting JAK2 acts to suppress hematopoiesis, consequently reducing red blood cell, neutrophil, platelet, and lymphocyte production. JAK2 inhibitors have been shown to be efficacious in treating various JAK-dependent hematologic malignancies, including the treatment of PV. By selective reduction of JAK2 levels, the ASO VGT-1849A has the potential t
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VNDA
News
- Vanda Pharmaceuticals Inc. (NASDAQ: VNDA) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $18.00 price target on the stock.MarketBeat
- Vanda Pharmaceuticals Announces Orphan Drug Designation Granted for VGT-1849A, a Novel and Selective Antisense Oligonucleotide Candidate for the Treatment of Polycythemia VeraPR Newswire
- Vanda Pharmaceuticals Inc. (NASDAQ: VNDA) is now covered by analysts at StockNews.com. They set a "hold" rating on the stock.MarketBeat
- Glancy Prongay & Murray LLP Announces Investigation of Vanda Pharmaceuticals Inc.Business Wire
- Vanda Pharmaceuticals Inc. (NASDAQ: VNDA) is now covered by analysts at StockNews.com. They set a "hold" rating on the stock.MarketBeat
VNDA
Earnings
- 11/6/24 - Beat
VNDA
Sec Filings
- 11/18/24 - Form 4
- 11/14/24 - Form 144
- 11/7/24 - Form 10-Q
- VNDA's page on the SEC website