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Stock impact report

Results of Phase I trial shed positive light on UNI-494 for acute kidney injury [Yahoo! Finance]

Unicycive Therapeutics, Inc. (UNCY) 
Company Research Source: Yahoo! Finance
Unicycive Therapeutics recently announced positive results from its Phase I trial of UNI-494, [a patented pro-drug of nicorandil which is currently in development for the treatment of acute kidney injury (AKI)]. Its use was shown to be safe and well-tolerated in both single ascending and multiple ascending doses. The trial results also showed that its absorption was fast and rapidly metabolised, and that plasma concentration increases when dose increases. The ageing global population will lead to an increase in the prevalence of AKI, leading to an expansion of the market as well as a growing need for more therapeutic options. Key opinion leaders interviewed by GlobalData have emphasised that a drug that specifically shows enhanced efficacy in kidney disease patients will most likely receive breakthrough or fast track designations and gain market share. UNI-494 exhibits therapeutic intervention activating the SUR2 subunit of the mitochondrial ATP-sensitive potassium channel (KATP Show less Read more
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