Tonix Pharmaceuticals reports positive topline trial outcomes of TNX-1500 [Yahoo! Finance]
Tonix Pharmaceuticals Holding Corp. (TNXP)
Last tonix pharmaceuticals holding corp. earnings: 3/24 05:15 pm
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Source: Yahoo! Finance
Fri, February 7, 2025 at 5:43 PM GMT+1 2 min read In This Article TNXP Tonix Pharmaceuticals has reported positive topline outcomes from its Phase I single ascending dose study of its crystallisable fragment (Fc)-modified humanised anti-CD40 ligand (CD40L) monoclonal antibody, TNX-1500, in healthy subjects. The trial aimed to evaluate the tolerability, safety, pharmacodynamics, and pharmacokinetics of the intravenous form of the antibody, to support dosing for a subsequent Phase II trial in recipients of kidney transplants. During the trial, TNX-1500 was administered intravenously to subjects at doses of 3mg/kg, 10mg/kg, and 30mg/kg for one hour. Subjects were monitored for one day post-infusion and attended periodic clinic visits for up to 120 days. To assess the therapy's immune modulation potency, a Keyhole Limpet Hemocyanin (KLH) challenge was administered on day 2 and day 29. Across three cohorts, 26 subjects were enrolled, and 24 completed the trial. The thera
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News
- Tonix Pharmaceuticals Announces Licensing TNX-4900, a Selective Sigma-1 Receptor Antagonist for Chronic Neuropathic Pain from Rutgers University [Yahoo! Finance]Yahoo! Finance
- Tonix Pharmaceuticals Announces Licensing TNX-4900, a Selective Sigma-1 Receptor Antagonist for Chronic Neuropathic Pain from Rutgers UniversityGlobeNewswire
- Tonix Pharmaceuticals Appoints Irina Ishak as General CounselGlobeNewswire
- Tonix Pharmaceuticals Announces FDA IND Clearance for Phase 2 Study of TNX-102 SL for the Treatment of Major Depressive DisorderGlobeNewswire
- Tonix Pharmaceuticals Announces U.S. Commercial Availability of TONMYA™ (cyclobenzaprine HCl sublingual tablets) as a First-in-Class Fibromyalgia Treatment [Yahoo! Finance]Yahoo! Finance
TNXP
Earnings
- 11/10/25 - In-Line
TNXP
Sec Filings
- 12/16/25 - Form 8-K
- 12/9/25 - Form 8-K
- 11/24/25 - Form 8-K
- TNXP's page on the SEC website