Medivir's licensee, Tango Therapeutics, has discontinued development of its TNG348 clinical program [Yahoo! Finance]
Tango Therapeutics, Inc. (TNGX)
Company Research
Source: Yahoo! Finance
for cancer in areas of high unmet medical need, announced today that Medivir's licensee, Tango Therapeutics (NASDAQ: TNGX; Tango), has announced that the phase 1/2 clinical trial of TNG348, a novel USP1 inhibitor, is being terminated due to toxicity observed in the initial study cohorts. TNG348 is a novel USP1 (ubiquitin-specific protease 1) inhibitor, for the treatment of BRCA1/2-mutant and other homologous recombination deficiency (HRD)+ cancers, and has been developed by Tango from the preclinical USP1 program licensed from Medivir in 2020. At present, Medivir has no additional information than what has been announced in Tango's press release: https://ir.tangotx.com/news-releases/news-release-details/tango-therapeutics-announces-discontinuation-tng348-program The announcement by Tango Therapeutics has no impact on Medivir's focus and development efforts with its lead program fostroxacitabine bralpamide (fostrox) for the treatment of primary liver cancer (HCC). Medivir continues
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TNGX
News
- Tango Therapeutics (TNGX) Moves 10.3% Higher: Will This Strength Last? [Yahoo! Finance]Yahoo! Finance
- Tango Therapeutics to Present at the Goldman Sachs 45th Annual Global Healthcare ConferenceBusiness Wire
- Tango Therapeutics, Inc. (NASDAQ: TNGX) was upgraded by analysts at Guggenheim to a "strong-buy" rating.MarketBeat
- Tango Therapeutics, Inc. (NASDAQ: TNGX) had its price target lowered by analysts at HC Wainwright from $16.00 to $13.00. They now have a "buy" rating on the stock.MarketBeat
- Tango Therapeutics, Inc. (NASDAQ: TNGX) had its price target lowered by analysts at Guggenheim from $16.00 to $14.00. They now have a "buy" rating on the stock.MarketBeat
TNGX
Earnings
- 11/8/23 - Beat
TNGX
Sec Filings
- 6/7/24 - Form 4
- 6/7/24 - Form 4
- 6/7/24 - Form 4
- TNGX's page on the SEC website