Tectonic Therapeutic reports findings from Phase Ia trial of TX45 [Yahoo! Finance]
Tectonic Therapeutic, Inc. (TECX)
Company Research
Source: Yahoo! Finance
A strong PK/PD relationship was established to identify Phase II doses and dosing regimens by assessing the change in renal plasma flow from baseline at various time points after dosing. In preclinical chronic pulmonary hypertension models, trough exposures associated with maximal activity also showed near-peak renal plasma flow increase on administering TX45. The PK/PD model derived from the Phase Ia data closely matched the relationship observed in preclinical studies when adjusted for potency differences between species, the company noted. Based on these models, Tectonic selected dose regimens for the Phase II proof of concept clinical trial in PH-HFpEF patients. The Phase II trial will randomise patients to 300mg subcutaneously once monthly, 300mg every other week, or placebo. Following the receipt of the US Food and Drug Administration's clearance of the investigational new drug application for TX45, subject screening in the Phase II APEX trial has commenced. The com
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TECX
News
- Tectonic Therapeutic (NASDAQ: TECX) is now covered by analysts at Raymond James. They set an "outperform" rating and a $65.00 price target on the stock.MarketBeat
- Tectonic Therapeutic Inc. Reports Q3 2024 Results [Yahoo! Finance]Yahoo! Finance
- Tectonic Therapeutic (NASDAQ: TECX) had its price target raised by analysts at Wells Fargo & Company from $55.00 to $79.00. They now have an "overweight" rating on the stock.MarketBeat
- Tectonic Therapeutic (NASDAQ: TECX) had its price target raised by analysts at Leerink Partners from $49.00 to $69.00. They now have an "outperform" rating on the stock.MarketBeat
- Tectonic Therapeutic Announces Positive Phase 1a Results in AHA 2024 Presentation for TX45, a Long-acting, Fc-Relaxin Fusion ProteinGlobeNewswire
TECX
Sec Filings
- 11/14/24 - Form SC
- 11/12/24 - Form 10-Q
- 11/7/24 - Form 8-K
- TECX's page on the SEC website