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0.000250062515628857 -0.00552388097024257 0.00125031257814446 0.0248862215553888 0.233058264566142 0.313953488372093 0.264816204051013 0.431607901975494
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Tectonic Therapeutic Announces Positive Interim Data from Phase 1b Trial for TX45 in Patients with Group 2 Pulmonary Hypertension in HFpEF [Yahoo! Finance]

Tectonic Therapeutic, Inc. (TECX) 
Company Research Source: Yahoo! Finance
Tectonic Therapeutic Thu, January 30, 2025 at 12:30 PM GMT+1 11 min read In This Article TECX Tectonic Therapeutic TX45 improved both left ventricular function and pulmonary hemodynamics in patients with Group 2 Pulmonary Hypertension in Heart Failure with preserved Ejection Fraction (“PH-HFpEF”), supporting endpoints and patient population in ongoing APEX Phase 2 clinical trial Interim analysis demonstrated that TX45 achieved 17.9% reduction in Pulmonary Capillary Wedge Pressure (“PCWP”) in the total study population of PH-HFpEF and 30% reduction in Pulmonary Vascular Resistance (“PVR”) in Combined pre- and post-capillary PH (“CpcPH”), a subpopulation with more severe disease TX45 was well tolerated in patients with PH-HF Read more
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