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-0.00561797752808985 -0.0161516853932584 -0.0161516853932584 0.0031601123595506 0.0129915730337078 0.0351123595505618 0.0533707865168539 0.0607443820224719
Stock impact report

Syros Stock Plunges as Lead Cancer Study Fails to Meet Primary Goal [Yahoo! Finance]

Syros Pharmaceuticals, Inc. (SYRS) 
Last syros pharmaceuticals, inc. earnings: 3/5 06:57 am Check Earnings Report
US:NASDAQ Investor Relations: ir.syros.com
Company Research Source: Yahoo! Finance
higher-risk myelodysplastic syndrome (HR-MDS) failed to meet the primary endpoint of complete response (CR) rate. Tamibarotene is Syros' proprietary, oral, selective RARa agonist. The phase III SELECT-MDS-1 study evaluated tamibarotene in combination with azacitidine, a chemotherapy, in newly diagnosed HR-MDS patients with RARa gene overexpression. Per the data readout, the CR rate in the first 190 enrolled patients in the tamibarotene/azacitidine treatment arm was 23.8%, which failed to demonstrate statistical significance over the CR rate of 18.8% observed in the placebo/azacitidine control arm. However, Syros reported that the combo drug was well-tolerated by the total enrolled HR-MDS patient population in the SELECT-MDS-1 study. Moreover, the treatment-related adverse events were similar to those observed in earlier company-sponsored studies. Year to date, shares of SYRS have plunged 95.4% compared with the industry's 3.8% decline. Image Source: Zacks Investment Research Show less Read more
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