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Stock impact report

Savara: Trial Successful, But I'm Only Half Convinced [Seeking Alpha]

Savara, Inc. (SVRA) 
Last savara, inc. earnings: 3/12 04:05 pm Check Earnings Report
Company Research Source: Seeking Alpha
Summary Savara's Molgramostim, a GM-CSF therapy, succeeded in a phase 3 trial for treating aPAP, a rare autoimmune lung condition, after a previous failure. The current standard treatment, WLL, is effective but complex, costly, and invasive, making GM-CSF a potentially preferable alternative despite its high price. Despite meeting primary endpoints in IMPALA-2, concerns remain about endpoint changes and high costs, making the investment risky. With a cash runway into 2026, Savara faces challenges convincing the market and FDA of Molgramostim's superiority. Hiroshi Watanabe Savara Inc. ( NASDAQ: SVRA ) is developing Molgramostim, "a non-glycosylated form of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF)," in a nebulizer formulation. The target indication is a rare disease called Autoimmune Pulmonary Alveolar Proteinosis (aPAP), a form of PAP. I covered SVRA in , when it did not have data, and then again in , when it had already failed its phase Show less Read more
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