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Stock impact report

SRPT Provides Pipeline Updates on Rare Muscular Disorder Therapies [Yahoo! Finance]

Sarepta Therapeutics, Inc. (SRPT) 
Last sarepta therapeutics, inc. earnings: 2/26 04:05 pm Check Earnings Report
Company Research Source: Yahoo! Finance
Following positive FDA feedback, the company is advancing a fourth LGMD program to clinical development. Sarepta will soon start screening and dosing patients in the first-in-human clinical SRP-9005-101 (COMPASS) study, to evaluate its investigational gene therapy SRP-9005 for LGMD type 2C/R5 (LGMD2C/R5, or gamma-sarcoglycanopathy). SRPT also announced completion of enrollment and dosing in the phase I proof-of-concept SRP-9004-102 (DISCOVERY) study, which is evaluating SRP-9004 in patients with LGMD type 2D/R3 (LGMD2D/R3, or alpha-sarcoglycanopathy). The company also reiterated its plans to report data from the late-stage EMERGENE study, evaluating SRP-9003 in patients with LGMD type 2E/R4 (LGMD2E/R4, or beta-sarcoglycanopathy), by first-half 2025. This study's primary endpoint is the biomarker expression of the beta-sarcoglycan protein, whose absence is the sole cause of the disease. Following a pre-BLA meeting, the FDA has confirmed eligibility for the accelerated approval pat Show less Read more
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