Spero Therapeutics Announces Publication of SPR720 Phase 1 Lung Exposure Data in Antimicrobial Agents and Chemotherapy
Spero Therapeutics, Inc. (SPRO)
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Source: GlobeNewswire
CAMBRIDGE, Mass., Oct. 02, 2024 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a multi-asset clinical-stage biopharmaceutical company, focused on identifying and developing novel treatments for rare diseases and multi-drug resistant (MDR) bacterial infections, today announced the publication of data from its Phase 1 clinical trial, which assessed the intrapulmonary pharmacokinetics (PK) of SPR719. The full manuscript, titled “Intrapulmonary pharmacokinetics of SPR719 following oral administration of SPR720 to healthy volunteers” was published ahead of print in Antimicrobial Agents and Chemotherapy. A copy of the paper can be accessed here. SPR720 is an oral, chemically stable phosphate ester prodrug that is converted rapidly in vivo to SPR719, the active moiety. SPR719 targets the ATPase site of DNA gyrase B in mycobacteria, a mechanism that is distinct from that of other antibiotics in use for Non Tuberculous Mycobacterial- Pulmonary Disease (NTM-PD). “The Phase 1 s
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SPRO
News
- Spero Therapeutics Announces SPR720 Phase 2a Interim Results and Provides a Business UpdateGlobeNewswire
- Spero Therapeutics, Inc. (NASDAQ:SPRO) Stock Has Shown Weakness Lately But Financials Look Strong: Should Prospective Shareholders Make The Leap? [Yahoo! Finance]Yahoo! Finance
- Spero Therapeutics Announces Presentation of SPR719 (Active Moiety of SPR720) In Vitro Data Demonstrating Low Propensity for the Development of Resistance at IDWeek 2024GlobeNewswire
- Spero Therapeutics, Inc. (NASDAQ: SPRO) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $7.00 price target on the stock.MarketBeat
- Spero Therapeutics to Present at Upcoming September Investor ConferencesGlobeNewswire
SPRO
Earnings
- 8/5/24 - Beat
SPRO
Sec Filings
- 10/29/24 - Form 8-K
- 9/10/24 - Form 8-K
- 8/29/24 - Form 4
- SPRO's page on the SEC website