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0.0930232558139536 0.10077519379845 0.0834108527131784 0.0310077519379845 0.0155038759689923 0.0155038759689923 0.0155038759689923 -0.0155038759689923
Stock impact report

Spero Therapeutics Announces Publication of SPR720 Phase 1 Lung Exposure Data in Antimicrobial Agents and Chemotherapy

Spero Therapeutics, Inc. (SPRO) 
Last spero therapeutics, inc. earnings: 3/16 08:45 am Check Earnings Report
US:NASDAQ Investor Relations: investors.sperotherapeutics.com/overview
Company Research Source: GlobeNewswire
CAMBRIDGE, Mass., Oct. 02, 2024 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a multi-asset clinical-stage biopharmaceutical company, focused on identifying and developing novel treatments for rare diseases and multi-drug resistant (MDR) bacterial infections, today announced the publication of data from its Phase 1 clinical trial, which assessed the intrapulmonary pharmacokinetics (PK) of SPR719. The full manuscript, titled “Intrapulmonary pharmacokinetics of SPR719 following oral administration of SPR720 to healthy volunteers” was published ahead of print in Antimicrobial Agents and Chemotherapy. A copy of the paper can be accessed here. SPR720 is an oral, chemically stable phosphate ester prodrug that is converted rapidly in vivo to SPR719, the active moiety. SPR719 targets the ATPase site of DNA gyrase B in mycobacteria, a mechanism that is distinct from that of other antibiotics in use for Non Tuberculous Mycobacterial- Pulmonary Disease (NTM-PD). “The Phase 1 s Show less Read more
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