Sonnet BioTherapeutics Announces Updated Clinical Data for SON-1010 as Monotherapy or Combined with an anti-PD-L1, along with an Increase in the Dose-Escalation Target [Yahoo! Finance]
Sonnet BioTherapeutics Holdings, Inc. (SONN)
Company Research
Source: Yahoo! Finance
Patients have received up to 25 cycles of SON-1010 as monotherapy and 10 cycles of SON-1010 with atezolizumab (Tecentriq ® ) without dose-limiting toxicity at any dose level Cytokine data reveals about 10-fold extended half-life for SON-1010 compared with rhIL-12 that induces prolonged and controlled IFNγ responses, with no evidence of cytokine release syndrome at any dose Clinical benefit was seen at four months post-initiation of dosing in 35% of evaluable patients (8/23) with advanced solid tumors PRINCETON, NJ / ACCESSWIRE / May 20, 2024 / Sonnet BioTherapeutics Holdings, Inc. (NASDAQ:SONN) (the "Company" or "Sonnet"), a clinical-stage company developing targeted immunotherapeutic drugs, announced today that the safety of SON-1010 dosing has been formally reviewed in both of the current Phase 1 clinical trials and the Company is now increasing the target dose of SON-1010 during dose escalation. SON-1010 is a proprietary version of recombinant human interleukin-12
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News
- Sonnet BioTherapeutics Announces Exercise of Warrants for $3.4 Million in Gross Proceeds [Yahoo! Finance]Yahoo! Finance
- Sonnet BioTherapeutics Announces Exercise of Warrants for $3.4 Million in Gross ProceedsGlobeNewswire
- Sonnet BioTherapeutics Announces the Generation and Characterization of Two Novel Immunotherapeutic Pipeline Drug Candidates, SON-1411 and SON-1400, Each Containing a Variant IL-18 Domain [Yahoo! Finance]Yahoo! Finance
- Sonnet BioTherapeutics Announces the Generation and Characterization of Two Novel Immunotherapeutic Pipeline Drug Candidates, SON-1411 and SON-1400, Each Containing a Variant IL-18 DomainGlobeNewswire
- Sonnet BioTherapeutics to Present SB221 as a Trial in Progress at the ASCO 2024 Annual Meeting [Yahoo! Finance]Yahoo! Finance
SONN
Sec Filings
- 6/20/24 - Form 8-K
- 6/14/24 - Form 8-K
- 6/13/24 - Form 8-K
- SONN's page on the SEC website