Boston Biomedical, Inc. Announces First Patient Dosed in Phase 1 Study of Investigational Agent TP-3654 in Patients with Myelofibrosis
SUMITOMO CHEM UNSP/ADR (SOMMY)
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Source: PR Newswire
CAMBRIDGE, Mass., April 6, 2020 /PRNewswire/ -- Boston Biomedical, Inc. today announced the first patient has been dosed in a phase 1 study evaluating the investigational agent TP-3654, a PIM kinase inhibitor, in patients with intermediate-2 and high-risk primary or secondary myelofibrosis. The multicenter, open-label, dose-escalation study will identify the maximum tolerated dose (MTD) and recommended phase 2 dose as well as assess the overall safety of oral TP-3654 as a monotherapy administered in patients with myelofibrosis who have been previously treated and failed or are ineligible to receive treatment with a Janus kinase (JAK) inhibitor. "The initiation of this study marks an important milestone for our company as we continue to advance our oncology portfolio of investigational compounds into the clinical setting. Also, it is the first compound originating from our affiliate, Tolero Pharmaceuticals, that Boston Biomedical will develop," said Patricia S. Andrews, Chief Executive
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