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Stock impact report

Sanofi licenses immune disease drugs from startup Earendil [Yahoo! Finance]

Sanofi - American Depositary Shares (SNY) 
US:NYSE Investor Relations: sanofi.com/en/investors
Company Research Source: Yahoo! Finance
French drugmaker Sanofi agreed to pay $125 million to startup Earendil Labs for two drug candidates designed to treat autoimmune and inflammatory bowel diseases. Under the terms of the deal announced Thursday , Earendil may receive as much as $1.72 billion in additional payments for reaching certain development and commercial goals, including $50 million described as a “near-term payment.” The startup will also be eligible for royalties if the drugs reach the market. The candidates, HXN-1002 and HNX-1003, are bispecific antibodies designed to engage two different proteins in the body involved in inflammation and immune cell activation. HXN-1002 is being developed for patients with ulcerative colitis and Crohn's disease. HXN-1003 has shown promise in preclinical models of colitis and skin inflammation, Earendil said. Dual-targeting antibodies have drawn considerable interest from pharmaceutical companies in recent years. But while much of the early activity centered around oncol Show less Read more
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