Skye Bioscience Demonstrates Prominent Role of Peripheral CB1 Inhibition and Achieves Significant Weight Loss with Novel CB1-inhibiting Antibody, Nimacimab, in Preclinical Model
Skye Bioscience, Inc. (SKYE)
Company Research
Source: GlobeNewswire
Peripherally-restricted nimacimab achieves significant dose-dependent weight loss, fat mass reduction, lean mass preservation, and glycemic control in diet-induced obesity model Preliminary data shows that nimacimab achieves desired metabolic outcomes without central inhibition and its risk of neuropsychiatric adverse events SAN DIEGO, Nov. 04, 2024 (GLOBE NEWSWIRE) -- Skye Bioscience, Inc. (Nasdaq: SKYE) (“Skye”), a clinical-stage biopharmaceutical company focused on unlocking new therapeutic pathways for metabolic health, today announced preliminary data from a diet-induced obesity (DIO) model in mice. Skye’s CB1-inhibiting antibody, nimacimab, achieved significant dose-dependent weight loss of up to 16% compared to vehicle, highlighting a novel peripherally-driven mechanism for inducing weight loss and other metabolic benefits. Skye developed a DIO model using a transgenic mouse expressing the human CB1 receptor (hCB1R). After establishing this newly-developed model, the goal
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News
- Skye Bioscience to Participate in Upcoming December Healthcare Investment ConferencesGlobeNewswire
- Skye Bioscience Surpasses 50% Patient Enrollment in Phase 2 Obesity Study of Differentiated CB1 Inhibitor [Yahoo! Finance]Yahoo! Finance
- Skye Bioscience Surpasses 50% Patient Enrollment in Phase 2 Obesity Study of Differentiated CB1 InhibitorGlobeNewswire
- Skye Bioscience Reports Third Quarter 2024 Financial Results and Recent HighlightsGlobeNewswire
- Skye Bioscience to Announce Third Quarter 2024 ResultsGlobeNewswire
SKYE
Earnings
- 11/7/24 - Beat
SKYE
Sec Filings
- 11/20/24 - Form 4
- 11/19/24 - Form 4
- 11/19/24 - Form 4
- SKYE's page on the SEC website