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Stock impact report

NIAID reports preliminary data from trial of SIGA's Mpox treatment [Yahoo! Finance]

SIGA Technologies Inc. (SIGA) 
US:NASDAQ Investor Relations: investor.siga.com/investor-relations
Company Research Source: Yahoo! Finance
from the PALM 007 clinical trial of SIGA Technologies' tecovirimat in treating monkeypox virus (Mpox). The placebo-controlled, randomised, double-blind trial assessed the safety and efficacy of oral tecovirimat along with standard of care (SOC). Patients from the Democratic Republic of the Congo (DRC) were randomly assigned in a 1:1 ratio to receive either oral tecovirimat plus SOC or a placebo plus SOC for 14 days. NIAID noted that the study did not meet its primary endpoint of a statistically significant improvement in time-to-lesion resolution within 28 days post-randomisation. However, a meaningful improvement was observed in patients who began treatment within seven days of symptom onset and those with severe disease. In the trial, tecovirimat also exhibited a safety profile comparable with placebo. These findings were in line with various other studies on healthy subjects. SIGA Technologies CEO Diem Nguyen said: “We are highly encouraged by the PALM 007 study results Show less Read more
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