Shuttle Pharma's Selective HDAC Inhibitor Exhibits ATM Activation and Modulation of ER Expression Resulting in Substantial Growth Inhibition of Estrogen Receptor Positive Breast Cancer Cel...
Shuttle Pharmaceuticals Holdings, Inc. (SHPH)
Company Research
Source: Yahoo! Finance
development stage specialty pharmaceutical company focused on improving outcomes for cancer patients treated with radiation therapy (RT), today announced the publication of a manuscript reporting on the ability of one of the Company's HDAC inhibitor pre-clinical assets, SP-1-303, which exhibits ataxia-telangiectasia mutated protein (ATM) activation and modulation of estrogen receptor expression resulting in substantial growth inhibition of estrogen receptor positive breast cancer cells (ER + BC). The published manuscript, titled "Dual-targeting class I HDAC inhibitor and ATM activator, SP-1-303, preferentially inhibits estrogen receptor positive breast cancer cell growth,” reports the work of Dr. Mira Jung, Professor of Radiation Medicine at Georgetown University Medical Center, and Dr. Scott Grindrod, Shuttle Pharma's Principal Scientist, and was published in PLOS ONE, a peer-reviewed open access journal published by the Public Library of Science (PLOS). SP-1-303, initially disco
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SHPH
News
- Shuttle Pharma Expands Clinical Trial Site Enrollment for Phase 2 of Ropidoxuridine for Treatment of Patients with GlioblastomaGlobeNewswire
- Shuttle Pharma Announces Issuance of U.S. Patent for Selective Histone Deacetylase Inhibitors for the Treatment of Human DiseaseGlobeNewswire
- Shuttle Pharma Provides Second Quarter 2024 Corporate UpdateGlobeNewswire
- Shuttle Pharma Regains Compliance with Nasdaq Minimum Bid Price RequirementGlobeNewswire
- Shuttle Pharma Receives Notice of Nasdaq Non-Compliance with Listing Rule 5250(c)(1) [Yahoo! Finance]Yahoo! Finance
SHPH
Sec Filings
- 9/20/24 - Form S-1
- 9/16/24 - Form 424B3
- 9/13/24 - Form 8-K
- SHPH's page on the SEC website