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-0.0135256988277728 -0.00234445446348066 -0.00901713255184851 -0.0311992786293958 0.0270513976555455 0.0174932371505861 0.19224526600541 0.172407574391344
Stock impact report

Sage's oral depression therapy fails in late-stage trial; shares plunge [Reuters (UK)]

Sage Therapeutics, Inc. (SAGE) 
Last sage therapeutics, inc. earnings: 2/27 06:30 am Check Earnings Report
US:NASDAQ Investor Relations: investor.sagerx.com/investor-relations
Company Research Source: Reuters
Sage's oral depression therapy fails in late-stage trial; shares plunge - Reuters 2 Min Read (Reuters) - Sage Therapeutics Inc said on Thursday its experimental drug failed to improve condition of patients with severe depression in a late-stage study, setting up the drugmaker to lose about $4 billion in valuation when the market opens. The hotly anticipated data was expected to allow the company to widen its reach in the multi-billion dollar depression market it entered with its first-approved drug, Zulresso, for postpartum depression. SVB Leerink analyst Marc Goodman had said in a note ahead of the trial results that a late-stage trial failure would be a major disappointment to investors and a setback for the company as it would be the first “chink in the armor” in the Sage story. The oral therapy, SAGE-217, did not produce a statistically significant improvement in patients scored across 17 different parameters, including anxiety and insomnia, at the 15-day mark during the trial. SA Show less Read more
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