Sage Therapeutics Announces Topline Results from the Phase 2 DIMENSION Study of Dalzanemdor (SAGE-718) in the Treatment of Cognitive Impairment Associated with Huntington’s Disease
Sage Therapeutics, Inc. (SAGE)
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Source: Business Wire
The Phase 2 DIMENSION Study did not meet its primary endpointDalzanemdor was generally well-tolerated; no new safety signals were observedBased on these data, the Company does not plan further development of dalzanemdor CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sage Therapeutics, Inc. (Nasdaq: SAGE) today announced topline results from the Phase 2 DIMENSION Study of dalzanemdor (SAGE-718) in participants with cognitive impairment (CI) associated with Huntington’s Disease (HD). In the study, dalzanemdor did not demonstrate a statistically significant difference versus placebo on the primary endpoint, the change from baseline on the Symbol Digit Modalities Test (SDMT) at Day 84. Analyses of secondary endpoints did not demonstrate statistically significant or clinically meaningful differences in participants treated with dalzanemdor compared to placebo. Based on these results, the Company does not plan further development of dalzanemdor.“We are disappointed by the results of the DIMENSION St
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News
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SAGE
Earnings
- 10/29/24 - Miss
SAGE
Sec Filings
- 12/13/24 - Form 144
- 11/26/24 - Form 8-K
- 11/20/24 - Form 8-K
- SAGE's page on the SEC website