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Stock impact report

Recursion Announces First Patient Dosed in Phase 1 Clinical Study of REC-3565, a Selective MALT1 Inhibitor for Relapsed or Refractory B-cell Lymphomas

Recursion Pharmaceuticals, Inc. - Class A (RXRX) 
Company Research Source: GlobeNewswire
Salt Lake City, UT, April 08, 2025 (GLOBE NEWSWIRE) -- Recursion (Nasdaq: RXRX), a leading clinical stage TechBio company decoding biology to radically improve lives, today announced that the first patient has been dosed in the Phase 1 EXCELERIZE clinical study evaluating REC-3565 for the treatment of relapsed or refractory B-cell lymphomas. "REC-3565 showed durable tumor regressions in preclinical studies, both as a monotherapy and in combination with a BTK inhibitor. Leveraging our AI-powered Recursion OS platform, which combines physics-based modeling with molecular dynamics and hotspot analysis, we delivered a lead candidate in just 15 months," said Najat Khan, Chief R&D Officer and Chief Commercial Officer at Recursion. "Its allosteric design enhances potency, selectivity, and safety, potentially reducing liver toxicity risks associated with UGT1A1 inhibition seen in other MALT1 inhibitors. This is particularly promising for patients with B-cell malignancies, where unmet need Show less Read more
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