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Stock impact report

Foundation Medicine Announces Partnership with Repare Therapeutics to Provide Genomic Profiling Services to Support Clinical Trials and to Develop Companion Diagnostic for Lunresertib [Yah...

Repare Therapeutics Inc. - Common Shares (RPTX) 
Company Research Source: Yahoo! Finance
leading clinical-stage precision oncology company, to provide prospective genomic profiling to patients in Repare's ongoing Phase I/Ib MYTHIC study ( NCT04855656 ) of lunresertib alone or in combinations in genomically-defined patient populations. The companies are also exploring opportunities to develop FoundationOne ® CDx, a tissue-based comprehensive genomic profiling test, as a companion diagnostic for the lunresertib program. Lunresertib is a first-in-class, selective and potent oral small molecule inhibitor of PKMYT1, a cancer target Repare discovered and identified as synthetic lethal with CCNE1 amplification, FBXW7 and PPP2R1A alterations in solid tumors. Lunresertib is being evaluated alone and in combinations across several studies in the United States, Canada, European Union and United Kingdom. Repare has presented positive initial Phase 1 data, including compelling safety and anti-tumor activity, demonstrating proof of concept for lunresertib alone and in combination wit Show less Read more
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