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-0.002746061569591 -0.0215349038878451 -0.0345425639543286 -0.0489955195837549 -0.0388784506431565 -0.0432143373319844 -0.0461049284578696 -0.0128631305101894
Stock impact report

Repare Therapeutics Announces Positive Initial Data at ESMO GI from Phase 1 MINOTAUR Trial Evaluating Lunresertib in Combination with FOLFIRI

Repare Therapeutics Inc. - Common Shares (RPTX) 
Company Research Source: Business Wire
Overall response of 18.2% in heavily pretreated patients across gastrointestinal tumors with target alterations regardless of prior irinotecan exposureProlonged clinical benefit in patients with CRC, with 40% of irinotecan-naïve patients receiving treatment for greater than nine monthsPreliminary RP2D established as 60mg BID lunresertib continuous plus standard FOLFIRISafety profile of combination consistent with FOLFIRI alone CAMBRIDGE, Mass. & MONTREAL--(BUSINESS WIRE)--Repare Therapeutics Inc. (“Repare” or the “Company”) (Nasdaq: RPTX), a leading clinical-stage precision oncology company, today reported positive initial data from the ongoing Phase 1 MINOTAUR clinical trial evaluating lunresertib (RP-6306) in combination with FOLFIRI in patients with advanced solid tumors. The data are being presented in a mini oral presentation by Elisa Fontana, M.D., Ph.D., Medical Director, Sarah Cannon Research Institute UK at the European Society of Medical Oncology (ESMO) Gastrointestinal ( Show less Read more
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