Data Demonstrating ENPP1 Inhibition as a Therapeutic Approach for Later-onset Hypophosphatasia Presented at the American Society for Bone and Mineral Research 2024 Annual Meeting
Rallybio Corporation (RLYB)
Company Research
Source: Business Wire
NEW HAVEN, Conn.--(BUSINESS WIRE)--Rallybio Corporation (Nasdaq: RLYB), a clinical-stage biotechnology company translating scientific advances into transformative therapies for patients with devastating rare diseases, announced today that nonclinical data demonstrating ENPP1 inhibition as a therapeutic approach for the treatment of patients with hypophosphatasia (HPP) was presented at the American Society for Bone and Mineral Research (ASBMR) 2024 Annual Meeting. ASBMR is being held September 27 – 30, 2024 in Toronto, Canada.“From my team’s earlier work published in 2002 and 2005, we knew that ENPP1 could be a targetable molecule to modulate TNAP’s all-important substrate PPi. I am delighted that we have now been able to demonstrate the efficacy of this principle in our mouse model of later-onset HPP,” said José Luis Millán, Ph.D., Professor, Human Genetics Program at Sanford Children’s Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, and author of the s
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