Rallybio Announces Publication of Target-Mediated Drug Disposition Modeling and Simulations Informing the RLYB212 Dosing Regimen in Pregnant Women
Rallybio Corporation (RLYB)
Company Research
Source: Business Wire
— Dosing Regimen to be Evaluated in Recently Initiated RLYB212 Phase 2 Clinical Trial — NEW HAVEN, Conn.--(BUSINESS WIRE)--Rallybio Corporation (Nasdaq: RLYB), a clinical-stage biotechnology company translating scientific advances into transformative therapies for patients with devastating rare diseases, today announced the publication of a manuscript titled, “Informing Pregnancy Dose via Target-Mediated Drug Disposition Modeling and Simulations for a Recombinant Human Monoclonal Antibody,” in a special pregnancy themed issue of Clinical Pharmacology and Therapeutics: Pharmacometrics & Systems Pharmacology.“Selecting a dose to ensure the safety of participants in any clinical trial is paramount, and not least for pregnant women and their developing babies. However, pharmacological research in pregnant women is limited, and few clinical pharmacology models incorporate the dynamic physiological changes during pregnancy,” said Steven Ryder, MD, Chief Medical Officer of Rallybio. “The
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