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Stock impact report

Rigel enrols first participant in Phase Ib/II AML treatment regimen trial [Yahoo! Finance]

Rigel Pharmaceuticals, Inc. (RIGL) 
Last rigel pharmaceuticals, inc. earnings: 2/27 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.rigel.com
Company Research Source: Yahoo! Finance
with decitabine and venetoclax for patients with mutated isocitrate dehydrogenase-1 (mIDH1) acute myeloid leukaemia (AML). The multicentre, open-label, non-randomised study is sponsored and being carried out by The University of Texas MD Anderson Cancer Center (MD Anderson) in the US. The initial Phase Ib portion of the trial aims to establish the safety, tolerability, and recommended Phase II dose of oral or intravenously administered (IV) decitabine and venetoclax plus olutasidenib in mIDH1 R/R patients. Following Phase Ib, the Phase II part of the trial will involve 60 patients. This portion will focus on determining the complete remission rate among both newly diagnosed and relapsed/refractory (R/R) mIDH1 AML patients as its primary objective. REZLIDHIA is an oral small-molecule inhibitor targeting mIDH1, designed to reduce 2-hydroxyglutarate levels and promote normal differentiation of myeloid cells. It is currently approved for treating R/R mIDH1 AML. This trial is Show less Read more
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