J&J and Protagonist's icotrokinra scores in Phase IIb UC study [Yahoo! Finance]
Protagonist Therapeutics, Inc. (PTGX)
Last protagonist therapeutics, inc. earnings: 3/10 04:01 pm
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Source: Yahoo! Finance
IIb study in patients with moderately to severely active ulcerative colitis (UC). J&J conducted the ANTHEM-UC trial (NCT06049017) of icotrokinra, an investigational targeted oral peptide that selectively blocks the IL-23 receptor, which reported a clinical response rate of 63.5% in patients treated with the highest dose of icotrokinra after 12 weeks compared to 27% in the placebo arm, measured on the Mayo Score / Disease Activity Index (DAI). The study also met a key secondary endpoint, with 30.2% of patients in the high-dose group achieving clinical remission compared to 11.1% of placebo patients. Remission and response continued to improve through week 28. Other endpoints included symptomatic remission and endoscopic improvement. The ANTHEM-UC study evaluated three doses of once-daily icotrokinra, with the drug being well tolerated by the proportion of patients reporting one or more adverse events (AEs) being similar between the icotrokinra and placebo groups. Full data from
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PTGX
News
- Protagonist Therapeutics (NASDAQ:PTGX) had its "overweight" rating reaffirmed by analysts at Barclays PLC.MarketBeat
- Protagonist Therapeutics (NASDAQ:PTGX) had its "buy" rating reaffirmed by analysts at Citigroup Inc..MarketBeat
- Protagonist Therapeutics, Inc. (PTGX): A Bull Case Theory [Yahoo! Finance]Yahoo! Finance
- Protagonist Therapeutics (NASDAQ:PTGX) had its price target raised by analysts at Citigroup Inc. from $96.00 to $98.00. They now have a "buy" rating on the stock.MarketBeat
- Protagonist Therapeutics (NASDAQ:PTGX) had its price target raised by analysts at JPMorgan Chase & Co. from $68.00 to $81.00. They now have an "overweight" rating on the stock.MarketBeat
PTGX
Earnings
- 11/6/25 - Miss
PTGX
Sec Filings
- 11/24/25 - Form 4
- 11/19/25 - Form 4
- 11/14/25 - Form SCHEDULE
- PTGX's page on the SEC website