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Stock impact report

ATHA Stock Tanks as Alzheimer's Study Fails to Meet Primary Goal [Yahoo! Finance]

Prothena Corporation plc - Ordinary Shares (PRTA) 
Last prothena corporation plc - ordinary shares earnings: 2/12 04:05 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.prothena.com
Company Research Source: Yahoo! Finance
phase II/III LIFT-AD study evaluating its pipeline candidate, fosgonimeton, for the treatment of mild-to-moderate Alzheimer's disease (AD). The LIFT-AD study investigated once-daily fosgonimeton (40 mg) subcutaneous injection versus placebo over a treatment period of 26 weeks in mild-to-moderate AD patients. The study did not meet the primary endpoint which was the Global Statistical Test (GST), a combination of results from measures of cognition and function. The study also failed to meet the key secondary endpoints of changes in cognition and function, plasma biomarkers of neurodegeneration, protein pathology and neuroinflammation. Shares of Athira have increased 16.4% so far this year compared with the industry's growth of 0.6%. Image Source: Zacks Investment Research However, in pre-specified subgroups of patients with moderate AD or who are carriers of the APOE4 gene, cognition and function improved or stabilized in patients who received fosgonimeton compared to place Show less Read more
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