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Stock impact report

PainReform Provides Further Update on Phase 3 Clinical Trial of PRF-110 [Yahoo! Finance]

PainReform Ltd. - Ordinary Shares (PRFX) 
Company Research Source: Yahoo! Finance
TEL AVIV, Israel, Dec. 27, 2024 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX) (" PainReform " or the " Company "), a clinical-stage specialty pharmaceutical company focused on the reformulation of established therapeutics, today announced an update regarding its Phase 3 clinical trial evaluating PRF-110 in post-surgical pain management of patients undergoing bunionectomy. PainReform previously disclosed initial topline data from its Phase 3 clinical trial in which it reported that it demonstrated statistically significant superiority over placebo in reducing pain during the first 48 hours following surgery. Yet, at that time, data pertaining to the last 24-hour period of the 72-hour study follow-up was unclear, and efforts were made to resolve the incoherence and complete the analysis. Following further investigation, PainReform has determined that the data from the final 24-hour period could not be clarified to satisfy the study's primary endpoint 72 hours requirement, and Show less Read more
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