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0.0873786407766991 0.0679611650485437 -0.0684466019417475 -0.0598058252427185 -0.0479611650485438 0.0194174757281554 -0.0388349514563106 0.0221359223300972
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PainReform Announces Initial Topline Data for PRF-110 Phase 3 Clinical Trial

PainReform Ltd. - Ordinary Shares (PRFX) 
Company Research Source: GlobeNewswire
TEL AVIV, Israel, Nov. 20, 2024 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX) ("PainReform" or the "Company"), a clinical-stage specialty pharmaceutical company focused on the reformulation of established therapeutics, today announced the receipt of partial topline data from its contract research organization (CRO), Lotus Clinical Research ("Lotus"), for the Phase 3 clinical trial evaluating PRF-110 in post-surgical pain management of patients undergoing bunionectomy. Initial analysis of the topline data indicates that PRF-110 demonstrated statistically significant superiority over placebo in reducing pain during the first 48 hours following surgery. These findings underscore PRF-110's potential to provide effective pain relief during the critical early postoperative period. However, data pertaining to the subsequent 24-hour period, which is essential for assessing the primary endpoint of the trial, is currently unclear due to incoherence of the data. PainReform is ac Show less Read more
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