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0 0.0134903640256959 0.00085653104925056 -0.00214132762312634 -0.0107066381156317 -0.00428265524625268 -0.00963597430406853 -0.00428265524625268
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Ocugen Announces Compelling Preliminary Data for OCU410—a Single Dose Novel Modifier Gene Therapy to Treat Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration [Yahoo! Fina...

Ocugen, Inc. (OCGN) 
Company Research Source: Yahoo! Finance
discovering, developing, and commercializing novel gene and cell therapies, biologics, and vaccines, today announced positive preliminary efficacy and safety data from the Phase 1 dose-escalation portion of the Phase 1/2 OCU410 ArMaDa clinical trial for geographic atrophy (GA), secondary to dry age-related macular degeneration (dAMD). Key findings include: no drug-related serious adverse events, reduced lesion growth, preservation of retinal tissue, and—most importantly—there was a positive effect on the functional visual measure of low luminance visual acuity (LLVA). Currently, there are approximately three million people living with GA in the United States (U.S.) and Europe combined. Patients in the U.S. have only one option available, anti-complement therapy, which requires multiple injections and only addresses one aspect of the disease. There remains no treatment option for GA in Europe. The OCU410 Phase 1 trial is evaluating nine patients in three dose cohorts (low, medium, Show less Read more
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