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Virion Therapeutics Reports Positive First-in-human, First-in-class, Phase 1b Immunogenicity Data of VRON-0200, a Novel Checkpoint Modifier for HBV Functional Cure at EASL Congress [Yahoo!...

Ocean Biomedical, Inc. (OCEA) 
Company Research Source: Yahoo! Finance
patients following a single, low dose, prime-only intramuscular injection of VRON-0200 VRON-0200 was well tolerated, with no serious adverse events (SAEs), study patient discontinuations, or laboratory abnormalities observed in 870 patient days on treatment VRON-0200 induced CD8+ T cell responses in the majority (5 of 9) of patients Responses were observed even in patients with limited pre-existing immunity A 4-fold increase in T cell responses at Day 28 was observed in the 5 responders At Day 91, several patients maintained T cell responses above their pre-treatment values June 5, 2024 /PRNewswire/ -- Virion Therapeutics, LLC, a clinical-stage biotechnology company, developing novel T cell-based immunotherapies , today announced positive immunologic and continued safety and tolerability data, from the first-ever human study of its novel, first-in-class, checkpoint modifier immunotherapy, VRON-0200, for HBV functional cure, presented by Professor Ed Gane , M.D., from the U Show less Read more
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