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OmniAb Announces Publication of Scientific Paper on Heavy Chain-Only Single-Domain Antibody Chicken Platform in the Journal of Immunology [Yahoo! Finance]

OmniAb, Inc. (OABI) 
Company Research Source: Yahoo! Finance
EMERYVILLE, Calif., June 03, 2024 BUSINESS WIRE OmniAb, Inc. (NASDAQ: OABI) today announced the publication of a peer-reviewed paper titled "Chickens with a Truncated Light Chain Transgene Express Single-Domain H Chain-Only Antibodies in the Journal of Immunology demonstrating that chickens can be genetically engineered to produce functional heavy chain-only single-domain antibodies. sdAbs are produced naturally by camelids and have gained popularity as small, robust and highly modular building blocks for antibody discovery. While most other vertebrates use the standard heterodimeric IgG structure due to the pairing of heavy and light chains and do not produce sdAb format immunoglobulins, OmniAb's scientific team led this study to investigate if chickens can support an immune repertoire based upon a heavy chain-only scaffold. "Our team's published data provided the foundational work supporting the feasibility of the Company's next-generation transgenic chicken Omni dAb that produ Show less Read more
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