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Stock impact report

Novartis Reports Updated Positive Data From Phase III SMA Program [Yahoo! Finance]

Novartis AG (NVS) 
Last novartis ag earnings: 4/28 01:00 am Check Earnings Report
US:NYSE Investor Relations: novartis.com/investors
Company Research Source: Yahoo! Finance
IT) in a broad group of patients aged 2 to under 18 years with spinal muscular atrophy (SMA). OAV101 IT is an investigational, one-time gene therapy for patients with SMA. In the registrational phase III STEER study, OAV101 IT treatment resulted in a statistically significant 2.39-point improvement on the Hammersmith Functional Motor Scale Expanded (HFMSE) compared to a 0.51-point increase in the sham control group. HFMSE is a key measure of motor function and disease progression in SMA. Additionally, in the phase IIIb STRENGTH study, treatment with OAV101 IT demonstrated stabilization of motor function over 52 weeks of follow-up in patients who had previously discontinued treatment with Spinraza (nusinersen) or Roche 's RHHBY Read more
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