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Stock impact report

Intellia doses first subject in trial of nex-z for hereditary ATTRv-PN [Yahoo! Finance]

Intellia Therapeutics, Inc. (NTLA) 
Last intellia therapeutics, inc. earnings: 2/27 07:30 am Check Earnings Report
US:NASDAQ Investor Relations: ir.intelliatx.com/investor-overview
Company Research Source: Yahoo! Finance
This global trial builds on Phase I data indicating that nex-z, with a single dose, can significantly decrease serum transthyretin (TTR) levels. It is a double-blind, placebo-controlled trial tailored to assess the safety and efficacy of nex-z in approximately 50 ATTRv-PN subjects. Adult participants with this condition will be randomised to receive either one 55mg infusion of the therapy or a placebo, with the primary endpoint being a modified neuropathy impairment score and serum TTR level changes. Intellia Therapeutics CEO and president John Leonard said: “This milestone marks important progress toward our goal of completing the MAGNITUDE-2 clinical programme, and we are optimistic the study will enable us to demonstrate nex-z's potential to be the first to halt or reverse disease progression with a single dose in hereditary ATTR with polyneuropathy.” Previously referred to as NTLA-2001, nex-z is an in vivo 'CRISPR-based' therapy designed to inactivate the TTR gene encodin Show less Read more
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