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Stock impact report

Neurocrine touts long-term effectiveness of Ingrezza for Huntington's disease chorea [Seeking Alpha]

Neurocrine Biosciences, Inc. (NBIX) 
Last neurocrine biosciences, inc. earnings: 2/4 04:05 pm Check Earnings Report
Company Research Source: Seeking Alpha
chorea associated with Huntington's disease show it was effective irrespective of a patient's antipsychotic use. Results from the open-label KINECT-HD2 study. Sustained improvements in the Unified Huntington's Disease Rating Scale Total Maximal Chorea ( TMC ) score were seen in all patients regardless of antipsychotic use through week 104. Improvement in Huntington's chorea was observed as early as week 2 (TMC change from baseline, -3.4) at the starting dose of 40 mg. At week 4 with dosage up to 60 mg, the change was -4.6. At week 104 with a maintenance dose of up to 80 mg, the figure was -5.2. From week 6 onwards, more than half of participants and investigators rated symptoms as "much improved" or "very much improved." At Week 104, this was seen in 75.9% of participants from self reports and 73.6% based on clinician assessment. More on Neurocrine Biosciences Neurocrine: Buying Opportunity After Stock Price Drop On Schizophrenia Data Neurocrine Biosciences: Disappoint Show less Read more
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