Neurocrine's Phase II schizophrenia trial fails to meet primary endpoint [Yahoo! Finance]
Neurocrine Biosciences, Inc. (NBIX)
Last neurocrine biosciences, inc. earnings: 2/4 04:05 pm
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Source: Yahoo! Finance
The randomised, parallel-group, double-blind, placebo-controlled trial enrolled adults with cognitive impairment associated with schizophrenia (CIAS). It assessed the safety, efficacy and tolerability of the asset in these subjects. According to the findings, luvadaxistat did not offer improvement in cognitive impairment in schizophrenia patients in the ERUDITE study, a second Phase II trial of the asset. The study's failure to meet cognitive endpoints is said to contrast with the earlier INTERACT study's positive results, the company noted. The variability in cognitive measures and potential baseline characteristic imbalances across treatment arms have been cited as contributing factors to the latest outcomes. A selective inhibitor targeting d-amino acid oxidase (DAAO), luvadaxistat is designed to modulate NMDA receptor function in the brain, which is implicated in the cognitive deficits observed in schizophrenia. Neurocrine acquired the rights to develop and commerciali
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- Neurocrine Biosciences' (NASDAQ:NBIX) Strong Earnings Are Of Good Quality [Yahoo! Finance]Yahoo! Finance
- Neurocrine Biosciences Presents New KINECT®-HD Data Showing Consistent Efficacy Across 19 Subgroups and Improvements in Aspects of Emotional Health With INGREZZA® (valbenazine) CapsulesPR Newswire
- Neurocrine Biosciences to Participate at Investor Conferences in NovemberPR Newswire
NBIX
Earnings
- 10/30/24 - Beat
NBIX
Sec Filings
- 11/12/24 - Form 4
- 11/7/24 - Form 4
- 11/1/24 - Form 4
- NBIX's page on the SEC website